Publications

Benz MS, Scott IU, Murray TG, Kramer D, Toledano S. Complications of systemic chemotherapy as treatment for retinoblastoma. Arch Ophthalmol 2000; 118:577-8.

Benz MS, Scott IU, Flynn HW Jr, Gedde SJ. Retinal detachment in patients with a preexisting glaucoma drainage device: anatomic, visual acuity, and intraocular pressure outcomes. Retina 2002; 22:283-7.

Benz MS, Smiddy WE. Increased diode laser uptake in inner retinal layers after indocyanine green staining of the internal limiting membrane. Ophthalmic Surg Lasers Imaging 2003;
34:64-7.

Benz MS, Murray TG, Dubovy SR, Katz RS, Eifrig CW. Endophthalmitis caused by Mycobacterium chelonae abscessus after intravitreal injection of triamcinolone. Arch Ophthalmol 2003; 121:271-3.

Benz MS, Escalona-Caamano EM, Murray TG. Simultaneous presentation of retinopathy of prematurity and bilateral familial retinoblastoma in a premature infant. J Pediatr Ophthalmol Strabismus 2003; 40:98-100.

Benz MS, Glaser JS, Davis JL. Progressive outer retinal necrosis in immunocompetent patients treated initially for optic neuropathy with systemic corticosteroids. Am J Ophthalmol 2003; 135:551-3.

Sussman DA, Escalona-Benz E, Benz MS, et al. Comparison of retinoblastoma reduction for chemotherapy vs external beam radiotherapy. Arch Ophthalmol 2003; 121:979-84.

Escalona-Benz E, Benz MS, Briggs JW, Budenz DL, Parrish RK, Murray TG. Uveal melanoma presenting as acute angle closure glaucoma: a report of two cases. Am J Ophthalmol 2003; 136:756-8.

Escalona-Benz E, Benz MS, Murray TG, et al. Magnetically integrated microporous implant: safety and efficacy of secondary posting. Arch Ophthalmol 2003; 121:1596-1600.

Moshfeghi DM, Kaiser PK, Scott IU, Sears JE, Benz MS, et al. Acute endophthalmitis following intravitreal triamcinolone acetonide injection. Am J Ophthalmol 2003; 136:791- 6.

Raja D, Benz MS, Murray TG, Escalona-Benz EM, Markoe A. Salvage external beam radiotherapy of retinal hemangiomas secondary to von Hippel-Lindau disease: visual and anatomic outcomes. Ophthalmol 2004; 111:150-3.

Benz MS, Scott IU, Flynn HW Jr, Unonius N, Miller D. Endophthalmitis isolates and antibiotic sensitivities: a 6-year review of culture-proven cases. Am J Ophthalmol 2004; 137:38- 42.

Benz MS, Escalona-Benz EM, Murray TG, et al. Immediate postoperative use of a topical agent to prevent intraocular pressure elevation after pars plana vitrectomy with gas tamponade. Arch Ophthalmol 2004; 122:705-9.

Hartley KL, Benz MS. Retinal pigment epithelial tear associated with a serous retinal detachment in a patient with thrombotic thrombocytopenic purpura. Retina 2004; 24:806-8.

Schiedler V, Scott IU, Flynn HW Jr, Davis JL, Benz MS, Miller D. Culture-proven endogenous endophthalmitis: clinical features and visual acuity outcomes. Am J Ophthalmol 2004;
137:725-31.

Miller DM, Benz MS, Murray TG, Dubovy SR. Intraretinal calcification and osseous metaplasia in coats disease. Arch Ophthalmol 2004; 122:1710-2.

Westfall AC, Osborn A, Kuhl D, Benz MS, Mieler WF, Holz ER. Acute endophthalmitis
Incidence : Intravitreal triamcinolone. Arch Ophthalmol 2005; 123:1075-7.

Donaldson KE, Gorscak JJ, Budenz DL, Feuer W, Benz MS, Forster RK. Anterior chamber and sutured posterior chamber intraocular lenses in eyes with poor capsular support. Journal of Cataract and Refractive Surgery 2005; 31:903-9.

Iyer MN, He F, Wensel TG, Mieler WF, Benz MS, Holz ER. Clearance of intravitreal moxifloxacin. Invest Ophthalmol Vis Sci 2006; 47:317-9.

Albini TA, Benz MS, Coffee RE, et al. Optical coherence tomography of ididopathic juxtafoveal telangiectasia. Ophthalmic Surg Lasers Imaging 2006; 37:120-8.

Benz MS, Albini TA, Holz ER, et al. Short-term course of intraocular pressure after intravitreal injection of triamcinolone acetonide. Ophthalmology 2006; 113:1174-8.

Iyer MN, He F, Wensel TG, Mieler WF, Benz MS, Holz ER. Intravitreal clearance of moxifloxacin. Trans Am Ophthalmol Soc 2006;103:76-81.

Yeh S, Bourgeois K, Benz MS. Full-thickness eccentric macular hole following vitrectomy with internal limiting membrane peeling. Ophthalmic Surg Lasers Imaging 2007; 38:59-60.

Carvounis PE, Kopel A, Benz MS. Retinal pigment epithelium tears following ranibizumab for exudative age-related macular degeneration. Am J Ophthalmol. 2007; 143:504-5.

Benz MS, Brown DM. Anti-VEGF agents in the treatment of neovascular AMD. Expert Review of Ophthalmology, 2007; 2:459-65.

Smith SV, Benz MS, Brown DM. Cystoid macular edema secondary to albumin-bound paclitaxel therapy. Arch Ophthalmol. 2008 Nov; 126(11):1605-6.

Luviano DM, Benz MS, Kim RY, Fish RH, Wong TP, Kegley EN, Brown DM. Selected clinical comparisons of spectral domain and time domain optical coherence tomography. Ophthalmic Surg Lasers Imaging. 2009 May-Jun; 40(3):325-8.

Benz MS, Packo KH, Gonzalez V, Pakola S, Bezner D, Haller JA, Schwartz SD. A placebo-controlled trial of microplasmin intravitreous injection to facilitate posterior vitreous detachment before vitrectomy. Ophthalmology. 2010 Apr; 117(4):791-7.

Chen E, Brown DM, Wong TP, Benz MS, Kegley E, Cox J, Fish RH, Kim RY. Lucentis using Visudyne study: determining the threshold-dose fluence of verteporfin photodynamic therapy combined with intravitreal ranibizumab for exudative macular degeneration. Clin Ophthalmol. 2010 Oct 5; 4:1073-9

Chen E, Brown DM, Benz MS, Fish RH, Wong TP, Kim RY, Major JC. Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy (the “flying saucer” sign). Clin Ophthalmol. 2010 Oct 21; 4:1151-8.

Chen E, Benz MS, Fish RH, Brown DM, Wong TP, Kim RY, Major JC. Use of nepafenac (Nevanac) in combination with intravitreal anti-VEGF agents in the treatment of recalcitrant exudative macular degeneration requiring monthly injections. Clin Ophthalmol. 2010 Oct 28; 4:1249-52.

Stalmans P, Benz MS, Gandorfer A, Kampik A, Girach A, Pakola S, Haller JA; MIVI-TRUST Study Group. Enzymatic vitreolysis with ocriplasmin for vitreomacular traction and macular holes. N Engl J Med 2012 Aug 16; 367(7):606-15.

MUST Research Group. Risk of elevated intraocular pressure and glaucoma in patients with uveitis: results of the multicenter uveitis steroid treatment trial. Ophthalmology 2013;120:1571-AREDS 2 Study Group. Methods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 Report Number 2). Invest Ophthalmol Vis Sci. 2013;54:4548-54.

Mariani AF, Major JC Jr., Brown DM, Wykoff CC, Benz MS, Kegley EN. Purtscher-like retinopathy associated with pemphigus vulgaris. Retin Cases Brief Rep. 2013;7:304-6.

Kempen JH, Sugar EA, Jaffe GJ, et al. Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema. Ophthalmology 2013;120:1852-9.

Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Cost-Effectiveness of fluocinolone acetonide implant versus systemic therapy for noninfectious intermediate, posterior, and panuveitis. Ophthalmology 2014;121:1855-62.

Haller JA, Stalmans P, Benz MS, et al. Efficacy of intravitreal ocriplasmin for treatment of vitreomacular adhesion: Subgroup analyses from two randomized trials. Ophthalmology 2014;122:117-122.

Gonzalez VH, Boyer DS, Schmidt-Erfurth U, Heier JS, Gordon C, Benz MS, et al. Microperimetric assessment of retinal sensitivity in eyes with diabetic macular edema from a phase 2 study of intravitreal aflibercept. Retina 2015;35:687-94.

Gandorfer A, Benz MS, Haller JA, et al. Association between anatomical resolution and functional outcome in the mivi-trust studies using ocriplasmin to treat symptomatic vitreomacular adhesion/vitreomacular traction, including when associated with macular hole. Retina 35:1151-7.

Li AL, Wykoff CC, Wong R, Chen E, Benz MS, et al. Endophthalmitis after intravitreal injection: Role of prophylactic topical ophthalmic antibiotics. Retina 2016;36:1349-56.

Birch DG, Benz MS, Miller DM, et al. Evaluation of full-field electroretinogram reductions after ocriplasmin treatment: Results of the OASIS trial ERG substudy. Retina 2018;38:364-78.

Payne JF, Clark WL, Bruce BB, Wykoff CC, Brown DM, Menke BM, Iverson SM, Allen KF, Boyer DS; Treat & Extend Protocol in Patients with Diabetic Macular Edema Study Group. Retinopathy Regression with Treat and Extend Ranibizumab for Diabetic Macular Edema. Ophthalmology. 2018 May 2. pii: S0161-6420(18)30678-X.PubMed PMID: 29729809.

P Mitchell, I McAllister, M Larsen, G Staurenghi, JF Korobelnik, MD, DS Boyer, DV Do, DM Brown, TA Katz, A Berliner, R Vitti, O Zeitz, C Metzig, C Lu, FG Holz. Evaluating the Impact of Intravitreal Aflibercept on Diabetic Retinopathy Progression in the VIVID-DME and VISTA-DME Studies. Ophthalmology Retina, 2018.

Brown DM, Ou WC, Wong TP, Kim RY, Croft DE, Wykoff CC; DAVE Study Group. Targeted Retinal Photocoagulation for Diabetic Macular Edema with Peripheral Retinal Nonperfusion: Three-Year Randomized DAVE Trial. Ophthalmology. 2018 May;125(5):683-690.PubMed PMID: 29336896.

Wykoff CC, Ou WC, Khurana RN, Brown DM, Lloyd Clark W, Boyer DS; ENDURANCE Study Group. Long-term outcomes with as-needed aflibercept in diabetic macular edema: 2-year outcomes of the ENDURANCE extension study. Br J Ophthalmol. 2018 May;102(5):631-636. PubMed PMID: 28814412.

Brown DM, Heier JS, Boyer DS, Freund KB, Kaiser P, Kim JE, Sarraf D. . Current Best Clinical Practices—Management of Neovascular AMD J. VitreoRetinal Diseases. 2017 1(5) 294-297.

Kwon S, Wykoff CC, Brown DM, van Hemert J, Fan W, Sadda SR. Changes in retinal ischaemic index correlate with recalcitrant macular oedema in retinal vein occlusion: WAVE study. Br J Ophthalmol. 2018 Apr 26. pii: bjophthalmol-2017-311475.PubMed PMID: 29699979.

Wykoff CC, Ou WC, Croft DE, Payne JF, Brown DM, Clark WL, Abdelfattah NS, Sadda SR; TREX-AMD Study Group. Neovascular age-related macular degeneration management in the third year: final results from the TREX-AMD randomised trial. Br J Ophthalmol. 2018 Apr;102(4):460-464. PubMed PMID: 28779006.

Brown DM, Wykoff CC. Intravitreal aflibercept for proliferative diabetic retinopathy. Lancet. 2017 Nov 11;390(10108):2141. PubMed PMID: 29143753.

Fan W, Wang K, Ghasemi Falavarjani K, Sagong M, Uji A, Ip M, Wykoff CC, Brown DM, van Hemert J, Sadda SR. Distribution of Nonperfusion Area on Ultra-widefield Fluorescein Angiography in Eyes With Diabetic Macular Edema: DAVE Study. Am J Ophthalmol. 2017 Aug;180:110-116. PubMed PMID: 28579062.

Jackson TL, Boyer DS, Brown DM,Chaudhry N, Elman M, Liang C, O’Shaughnessy D, Parsons E, Patel S, Slakter JS, Rosenfeld PJ. Oral tyrosine kinase inhibitor for neovascular age-related macular degeneration: a phase 1 Dose Escalation Study. JAMA Opthalmology- 2017 Jul 1;135(7):761-767. PubMed PMID: 28570723.

Wykoff CC, Ou WC, Wang R, Brown DM, Cone C, Zamora D, Le RT, Sagong M, Wang K, Sadda SR; WAVE Study Group.. Peripheral Laser for Recalcitrant Macular Edema Owing to Retinal Vein Occlusion: The WAVE Trial. Ophthalmology. 2017 Jun;124(6):919-921. PMID: 28318636.

Ou WC, Brown DM, Payne JF, Wykoff CC. Relationship Between Visual Acuity and Retinal Thickness During Anti-Vascular Endothelial Growth Factor Therapy for Retinal Diseases. Am J Ophthalmol. 2017 May 23. pii: S0002-9394(17)30216-7. PMID: 28549848.

Wykoff CC, Le RT, Khurana RN, Brown DM, Ou WC, Wang R, Clark WL, Boyer DS; ENDURANCE Study Group. Reply. Am J Ophthalmol. 2017 May;177:236-237. PubMed PMID: 28302270.

Ho AC, Albini TA, Brown DM, Boyer DS, Regillo CD, Heier JS. The Potential Importance of Detection of Neovascular Age-Related Macular Degeneration When Visual Acuity Is Relatively Good. JAMA Ophthalmol. 2017 Mar 1;135(3):268-273. PMID: 28114653.

Wykoff CC, Le RT, Khurana RN, Brown DM, Ou WC, Wang R, Clark WL, Boyer DS; ENDURANCE Study Group.. Outcomes With As-Needed Aflibercept and Macular Laser Following the Phase III VISTA DME Trial: ENDURANCE 12-Month Extension Study. Am J Ophthalmol. 2017 Jan;173:56-63. PMID: 27702624.

Payne JF, Wykoff CC, Clark WL, Bruce BB, Boyer DS, Brown DM; TREX-DME Study Group.. Randomized Trial of Treat and Extend Ranibizumab with and without Navigated Laser for Diabetic Macular Edema: TREX-DME 1 Year Outcomes. Ophthalmology. 2017 Jan;124(1):74-81. PMID: 27836430.

Wang R, Wykoff CC, Brown DM. Granular Hyper-reflective Specks by Spectral Domain Optical Coherence Tomography as a sign of West Nile Virus infection: The Stardust Sign Retin Cases Brief Rep. 2016 Fall;10(4):349-53. PMID: 26674277.

Heier JS, Korobelnik JF, Brown DM, Schmidt-Erfurth U, Do DV, Midena E, Boyer DS, Terasaki H, Kaiser PK, Marcus DM, Nguyen QD, Jaffe GJ, Slakter JS, Simader C, Soo Y, Schmelter T, Vitti R, Berliner AJ, Zeitz O, Metzig C, Holz FG. Intravitreal Aflibercept for Diabetic Macular Edema: 148-Week Results from the VISTA and VIVID Studies. Ophthalmology. 2016 Nov;123(11):2376-2385. PMID: 27651226.

Clark WL, Boyer DS, Heier JS, Brown DM, Haller JA, Vitti R, Kazmi H, Berliner AJ, Erickson K, Chu KW, Soo Y, Cheng Y, Campochiaro PA. Reply. Ophthalmology. 2016 Oct;123(10):e60-1. PubMed PMID: 27664917.

Wang R, Wykoff CC, Christie L, Croft DE, Major JC Jr, Fish RH, Brown DM.Choroidal Neovascularization Secondary to Alexandrite Laser Exposure. Retina Cases Brief Rep. 2016 Summer;10(3):244-8. PMID: 26584328.

Clark WL, Boyer DS, Heier JS, Brown DM, Haller JA, Vitti R, Kazmi H, Berliner AJ, Erickson K, Chu KW, Soo Y, Cheng Y, Campochiaro PA. Intravitreal Aflibercept for Macular Edema Following Branch Retinal Vein Occlusion: 52-Week Results of the VIBRANT Study. Ophthalmology. 2016 Feb;123(2):330-6. Epub 2015 Oct 30. PMID: 26522708.

Heier JS, Bressler NM, Avery RL, Bakri SJ, Boyer DS, Brown DM, Dugel PU, Freund KB, Glassman AR, Kim JE, Martin DF, Pollack JS, Regillo CD, Rosenfeld PJ, Schachat AP, Wells JA 3rd; American Society of Retina Specialists Anti-VEGF for Diabetic Macular Edema Comparative Effectiveness Panel. Comparison of Aflibercept, Bevacizumab, and Ranibizumab for Treatment of Diabetic Macular Edema: Extrapolation of Data to Clinical Practice. JAMA Ophthalmol. 2016 Jan 1;134(1):95-9. PMID: 26512939.

Wang R, Wykoff CC, Brown DM. Granular Hyperreflective Specks by Spectral Domain Optical Coherence Tomography as Signs of West Nile Virus Infection: The Stardust Sign. Retina Cases Brief Rep. 2015 Dec 13. PMID: 26674277.

Li AL, Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC Jr, Brown DM, Schefler AC, Kim RY, OʼMalley RE. Endophthalmitis after Intravitreal Injection-: Role of Prophylactic Topical Ophthalmic Antibiotics. Retina. 2015 Dec 11. PMID: 26655622.

Major JC Jr, Wykoff CC, Croft DE, Wang R, Mariani AF, Lehmann AE, Brown DM. Aflibercept for pigment epithelial detachment for previously treated neovascular age-related macular degeneration. Can J Ophthalmol. 2015 Oct;50(5):373-7. Epub 2015 Aug 12. PMID: 26455973.

Boyer DS, Nguyen QD, Brown DM, Basu K, Ehrlich JS; RIDE and RISE Research Group. Outcomes with As-Needed Ranibizumab after Initial Monthly Therapy: Long-Term Outcomes of the Phase III RIDE and RISE Trials. Ophthalmology. 2015 Dec;122(12):2504-2513. Epub 2015 Oct 9. PMID: 26452713.

Brown DM, Wykoff CC, Croft DE, Wong TP; RAVE Study Group. Reply: To PMID 24914476. Retina. 2015 Oct;35(10):e61-3 PMID: 26398558.

Wykoff CC, Croft DE, Brown DM, Wang R, Payne JF, Clark L, Abdelfattah NS, Sadda SR; TREX-AMD Study Group. Prospective Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: TREX-AMD 1-Year Results. Ophthalmology. 2015 Dec;122(12):2514-22. Epub 2015 Sep 29. PMID: 26391465.

Brown DM, Schmidt-Erfurth U, Do DV, Holz FG, Boyer DS, Midena E, Heier JS, Terasaki H, Kaiser PK, Marcus DM, Nguyen QD, Jaffe GJ, Slakter JS, Simader C, Soo Y, Schmelter T, Yancopoulos GD, Stahl N, Vitti R, Berliner AJ, Zeitz O, Metzig C, Korobelnik JF. Intravitreal Aflibercept for Diabetic Macular Edema: 100-Week Results From the VISTA and VIVID Studies. Ophthalmology. 2015 Oct;122(10):2044-52. Epub 2015 Jul 18. PMID: 26198808.

Croft DE, Wykoff CC, van Hemert J, Verhoek M, Brown DM. Not All Retina Is Created Equal: Metabolic Quantification of Ultra-Widefield Images. Ophthalmology. 2015 Dec;122(12):2580-2. Epub 2015 Jun 26. PMID: 26123089.

Brown DM, Korobelnik JF; VISTA and VIVID study investigators. Intravitreal aflibercept for diabetic macular edema. Ophthalmology. 2015 Jun;122(6):e38-9. PMID: 26008916.

Wykoff CC, Brown DM, Croft DE, Major JC Jr, Wong TP. Progressive Non-Perfusion in Ischemic Central Retinal Vein Occlusion. RETINA. 2015 Jan; 35(1): 43-7. PMID: 25102193.

Campochiaro PA, Clark WL, Boyer DS, Heier JS, Brown DM, Vitti R, Kazmi H, Berliner AJ, Erickson K, Chu KW, Soo Y, Cheng Y, Haller JA. Intravitreal Aflibercept for Macular Edema Following Branch Retinal Vein Occlusion: The 24-Week Results of the VIBRANT Study. Ophthalmology. 2015 Mar;122(3):538-44. PMID: 25315663.

Brown DM. Eight Questions with Dr. Puliafito. Ophthalmic Surg Lasers Imaging Retina. 2014 Jul 1;45(4):353-5. PMID: 25037016.

Croft DE, van Hemert J, Wykoff CC, Clifton D, Verhoek M, Fleming A, Brown DM. Precise montaging and metric quantification of retinal surface area from ultra-widefield fundus photography and fluorescein angiography. Ophthalmic Surg Lasers Imaging Retina. 2014 Jul-Aug 1;45(4):312-7. PMID: 25037013.

Korobelnik J-F, Do DV, Schmidt-Erfurth U, Boyer DS, Holz FJ, Heier JS, Midena E, Kaiser PK, Terasaki H, Marcus DM, Nguyen NJ, Jaffe GJ, Slakter JS, Simader C, Soo Y, Schmelter T, Yancopoulos GD, Stahl NS, Vitti R, Berliner AJ, Zeitz O, Metzig C, Brown DM. Intravitreal Aflibercept for Diabetic Macula Edema. Ophthalmology. 2014 Nov. 121(11):2247-54. Epub 2014 Jul 8. PMID: 25012934..

Brown DM, Wykoff CC, Wong TP, Mariani AF, Croft DE, Schuetzle K for the RAVE STUDY GROUP, Ranibizumab in Pre-Proliferative (Ischemic) Central Retinal Vein Occlusion (CRVO): The Rubeosis Anti- VEgf (RAVE) Trial. RETINA. 2014. Sep;34(9):1728-35 PMID: 24914476.

Heier JS, Clark WL, Boyer DS, Brown DM, Vitti R, Berliner AJ, Kazmi H, Ma Y, Stemper B, Zeitz O, Sandbrink R, Haller JA. Intravitreal aflibercept injection for macular edema due to central retinal vein occlusion: two-year results from the COPERNICUS study. Ophthalmology. 2014 Jul;121(7):1414-1420. Epub 2014 Mar 27. PMID: 24679444.

Karth PA, Raja SC, Brown DM, Kim JE. Outcomes of Macular Hole Surgeries for Macular Telangiectasia Type 2. RETINA. 2014 May;34(5):907-15. PMID: 24270919.

Wykoff CC, Brown DM, Maldonado ME, Croft DE. Aflibercept treatment for patients with exudative age-related macular degeneration who were incomplete responders to multiple ranibizumab injections (TURF trial). Br J Ophthalmol. 2014 Jul;98(7):951-5. Epub 2014 Feb 11. PMID: 24518078.

Takakura A, Tessler HH, Goldstein DA, Guex-Crosier Y, Chan CC, Brown DM, Thorne JE, Wang R, Cunningham ET Jr. Viral retinitis following intraocular or periocular corticosteroid administration: a case series and comprehensive review of the literature. Ocul Immunol Inflamm. 2014 Jun;22(3):175-82. PMID: 24655372.

Campochiaro PA, Sophie R, Pearlman J, Brown DM, Boyer DS, Heier JS, Marcus DM, Feiner L, Patel A; RETAIN Study Group. Long-term outcomes in patients with retinal vein occlusion treated with ranibizumab: the RETAIN study. Ophthalmology. 2014 Jan;121(1):209-19. PMID: 24112944.

Heier JS, Brown DM, Chong V, Korobelnik JF, Kaiser PK, Nguyen QD, Kirchhof B, Ho A, Ogura Y, Schmidt-Erfurth U. Author reply: To PMID 23084240. Ophthalmology. 2014 Jan;121(1):e5-e6. PMID: 24536092.

Major JC, Wykoff CC, Mariani AF, Chen E, Croft DE, Brown DM. Comparison of spectral-domain and time-domain optical coherence tomography in the detection of neovascular age related macular degeneration activity. RETINA. 2014 Jan;34(1):48-54. PMID: 23764967.

Schmidt-Erfurth U, Kaiser PK, Korobelnik JF, Brown DM, Chong V, Nguyen QD, Ho AC, Ogura Y, Simader C, Jaffe GJ, Slakter JS, Yancopoulos GD, Stahl N, Vitti R, Berliner AJ, Soo Y, Anderesi M, Sowade O, Zeitz O, Norenberg C, Sandbrink R, Heier JS. Intravitreal Aflibercept Injection for Neovascular Age-Related Macular Degeneration: Ninety-Six-Week Results of the VIEW Studies. Ophthalmology. 2014 Jan;121(1):193-201. Epub 2013 Sep 29. PMID: 24084500.

Wykoff CC, Brown DM, Croft DE, Wong TP. Two year SAVE (Super-dose anti-VEGF) outcomes: 2.0 mg ranibizumab for recalcitrant neovascular age-related macular degeneration. Ophthalmology. 2013 Sep;120(9):1945-1946. PMID: 24001533.

Mariani AF, Major JC Jr, Brown DM, Wykoff CC, Benz MS, Kegley EN. Purtscher-like retinopathy associated with pemphigus vulgaris. Retin Cases Brief Rep. 2013 Fall;7(4):304-6. PMID: 25383823.

Busbee BG, Ho AC, Brown DM, Heier JS, Suñer IJ, Li Z, Rubio RG, Lai P; HARBOR Study Group. Twelve-month efficacy and safety of 0.5 mg or 2.0 mg ranibizumab in patients with subfoveal neovascular age-related macular degeneration. Ophthalmology. 2013 May;120(5):1046-56. PMID: 23352196.

Campochiaro PA, Channa R, Berger BB, Heier JS, Brown DM, Fiedler U, Hepp J, Stumpp MT. Treatment of diabetic macular edema with a designed ankyrin repeat protein that binds vascular endothelial growth factor: a phase I/II study. American Journal Ophthalmology. 2013 Apr;155(4):697-704. PMID: 23218689.

Brown DM, Chen E, Mariani A, Major JC Jr; SAVE Study Group; Super-dose Anti-VEGF (SAVE) Trial: 2.0 mg Intravitreal Ranibizumab for Recalcitrant Neovascular Macular Degeneration-Primary End Point. Ophthalmology. 2013 Feb;120(2):349-54. PMID: 23131717 .

Wykoff CC, Brown DM, Chen E, Major JC, Croft DE, Mariani A, Wong TP. SAVE (Super-dose anti-VEGF) trial: 2.0 mg ranibizumab for recalcitrant neovascular age-related macular degeneration: 1-year results. Ophthalmic Surg Lasers Imaging Retina. 2013; 44(2):121-6. PMID: 23510037.

Brown DM, Nguyen QD, Marcus DM, Boyer DS, Patel S, Feiner L, Schlottmann PG, Rundle AC, Zhang J, Rubio RG, Adamis AP, Ehrlich JS, Hopkins JJ; RIDE and RISE Research Group. Long-term Outcomes of Ranibizumab Therapy for Diabetic Macular Edema: The 36-Month Results from Two Phase III Trials: RISE and RIDE. Ophthalmology. 2013 Oct; 120(10):2013-2022. PMID: 23706949.

Brown DM, Heier JS, Clark WL, Boyer DS, Vitti R, Berliner AJ, Zeitz O, Sandbrink R, Zhu X, Haller JA. Intravitreal aflibercept injection for macular edema secondary to central retinal vein occlusion: 1-year results from the phase 3 COPERNICUS study. American Journal Ophthalmology. 2013 Mar;155(3):429-437. PMID: 23218699.

Campochiaro PA, Nguyen QD, Hafiz G, Bloom S, Brown DM, Busquets M, Ciulla T, Feiner L, Sabates N, Billman K, Kapik B, Green K, Kane FE, FAMOUS Study Group. Aqueous levels of fluocinolone acetonide after administration of fluocinolone acetonide inserts or fluocinolone acetonide implants. Ophthalmology. 2013 Mar;120(3):583-7. PMID: 23218184.

Brown DM, Nguyen QD, Ehrlich JS; RISE and RIDE Research Group. Ranibizumab for diabetic macular edema. Author reply. Ophthalmology. 2013 Jan;120(1):221-2. PMID: 23283201.

Brown DM, Tuomi L, Shapiro H; For The Pier Study Group . Anatomical Measures as predictors of visual outcomes in ranibizumab-treated eyes with Neovascular Age-Related Macular Degeneration. RETINA. 2013 Jan;33(1):23-34. PMID: 23073338.

Heier JS, Brown DM, Chong V, Korobelnik JF, Kaiser PK, Nguyen QD, Kirchhof B, Ho A, Ogura Y, Yancopoulos GD, Stahl N, Vitti R, Berliner AJ, Soo Y, Anderesi M, Groetzbach G, Sommerauer B, Sandbrink R, Simader C, Schmidt-Erfurth U; VIEW 1 and VIEW 2 Study Groups. Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-Related Macular Degeneration. Ophthalmology. 2012 Dec;119(12):2537-48. PMID: 23084240.

Campochiaro PA, Brown DM, Pearson A, Chen S, Boyer D, Ruiz-Moreno J, Garretson B, Gupta A, Hariprasad SM, Bailey C, Reichel E, Soubrane G, Kapik B, Billman K, Kane FE, Green K; FAME Study Group. Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edema. Ophthalmology. 2012 Oct; 119(10):2125-32. PMID: 22727177.

Do DV, Nguyen QD, Boyer D, Schmidt-Erfurth U, Brown DM, Vitti R, Berliner AJ, Gao B, Zeitz O, Ruckert R, Schmelter T, Sandbrink R, Heier JS; DA VINCI Study Group. One-year outcomes of the DA VINCI Study of VEGF Trap-Eye in eyes with diabetic macular edema. Ophthalmology. 2012 Aug;119(8):1658-65. PMID: 22537617.

Boyer D, Heier J, Brown DM, Clark WL, Vitti R, Berliner AJ, Groetzbach G, Zeitz O, Sandbrink R, Zhu X, Beckmann K, Haller JA. Vascular endothelial growth factor Trap-Eye for macular edema secondary to central retinal vein occlusion: six-month results of the phase 3 COPERNICUS study. Ophthalmology. 2012 May;119(5):1024-32. PMID: 22440275.

Nguyen QD, **Brown DM**, Marcus DM, Boyer DS, Patel S, Feiner L, Gibson A, Sy J, Rundle AC, Hopkins JJ, Rubio RG, Ehrlich JS; RISE and RIDE Research Group. Ranibizumab for diabetic macular edema: results from 2 phase III randomized trials: RISE and RIDE. Ophthalmology. 2012 Apr;119(4):789-801.Co-First Author PMID: 22330964.

Chen E, Lin MY, Cox J, Brown DM. Endophthalmitis after intravitreal injection: the importance of Viridans Streptococci. RETINA. 2011 Sep; 31(8) 1525-33. PMID: 21878800.

Campochiaro PA, Brown DM, Awh CC, Lee SY, Gray S, Saroj N, Murahashi WY, Rubio RG. Sustained benefits of ranibizumab for macular edema following central retinal vein occlusion: 12-month outcomes of a phase III study. Ophthalmology. 2011 Oct; 118:(10) 2041-49. PMID: 21715011.

Brown DM, Campochiaro PA, Bhisitkul RB, Ho AC, Gray S, Saroj N, Adamis AP, Rubio RG, Murahashi WY. Sustained benefits of ranibizumab for macular edema following branch retinal vein occlusion: 12-month outcomes of a phase III study. Ophthalmology. 2011 Aug;118(8):1594-602 PMID: 21684606.

Zhang K, Hopkins JJ, Heier JS, Birch DG, Halperin LS, Albini TA, Brown DM, Jaffe GJ, Tao W, Williams GA. Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration. Proc Natl Acad Sci USA. 2011 Apr 12; 108(15) 6241-5. PMID: 21444807.

Heier JS, Boyer D, Nguyen QD, Marcus D, Roth DB, Yancopoulos G, Stahl N, Ingerman A, Vitti R, Berliner AJ, Yang K, Brown DM for the CLEAR-IT 2 Investigators 1-year Results of CLEAR-IT 2, a Phase 2 Study of Vascular Endothelial Growth Factor Trap-Eye Dosed As-needed After 12-week Fixed Dosing. Ophthalmology. 2011 Jun; 118(6) 1098-1106. PMID: 21640258.

Brown DM, JS Heier, Ciulla T, Ben M, Abraham P, Yancopoulos G, Stahl N, Ingerman A, Vitti R, Berliner AJ, Yang K, Nguyen QD, CLEAR-IT 2 Investigators. Primary Endpoint Results of a Phase 2 Study of Vascular Endothelial Growth Factor Trap-Eye in Wet Age-Related Macular Degeneration. Ophthalmology. 2011 Jun; 118(6) 1089-97. PMID: 21640257.

Campochiaro PA, Brown DM, Pearson A, Ciulla T, Boyer D, Holz FG, Tolentino M, Gupta A, Duarte L, Madreperia S, Gonder J, Kapik B, Billman K, Kane FE, FAME STUDY GROUP. Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic macular edema. Ophthalmology. 2011 Apr; 118(6) 626-35. PMID: 21459216.

Heier JS, Brown DM, Ciulla T, Abraham P, Bankert JM, Chong S, Daniel PE Jr, Kim IK. Ranibizumab for choroidal neovascularization secondary to causes other than age-related macular degeneration: a phase I clinical trial. Ophthalmology. 2011 Jan; 118(1) 111-8. PMID: 20678799.

Chen E, Brown DM, Wong TP, Benz MS, Kegley E, Cox J, Fish RH, Kim RY. Lucentis using Visudyne study: determining the threshold-dose fluence of Verteporfin photodynamic therapy combined with intravitreal ranibizumab for exudative macular degeneration. Clin Ophthalmol. 2010 Oct 5; 5(4) 1073-9. PMID: 20957143.

Chen E, Brown DM, Benz MS, Fish RH, Wong TP, Kim RY, Major JC. Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy (the "flying saucer" sign). Clin Ophthalmol. 2010 Oct 21; 4: 1151-8. PMID: 21060664.

Campochiaro PA, Hafiz G, Shah SM, Bloom S, Brown DM, Busquets M, Ciulla T, Feiner L, Sabates N, Billman K, Kapik B, Green K, Kane F; Famous Study Group. Sustained ocular delivery of fluocinolone acetonide by an intravitreal insert. Ophthalmology. 2010 Jul; 117(7) 1393-9. PMID: 20202684.

Chen E, Benz MS, Fish RH, Brown DM, Wong TP, Kim RY, Major JC. Use of nepafenac (Nevanac) in combination with intravitreal anti-VEGF agents in the treatment of recalcitrant exudative macular degeneration requiring monthly injections. Clin Ophthalmol. 2010 Oct 28; 4: 1249-52. PMID: 21151329.

Brown DM, Campochiaro PA, Singh RP, Li Z, Gray S, Saroj N, Rundle AC, Rubio RG, Murahashi WY. Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study. Ophthalmology. 2010 Jun; 117(6) 1124-1133. PMID: 20381871.

Boyer DS, Heier JS, Brown DM, Francom SF, Ianchulev T, Rubio RG. A Phase IIIb study to evaluate the safety of ranibizumab in subjects with neovascular age-related macular degeneration. Ophthalmology. 2009 Sep; 116(9) 1731-9. PMID: 19643495.

Luviano DM, Benz MS, Kim RY, Fish RH, Wong TP, Kegley EN, Brown DM. Selected clinical comparisons of spectral domain and time domain optical coherence tomography. Ophthalmic Surg Lasers Imaging. 2009 May-Jun; 40(3) 325-8. PMID: 19485303.

Brown DM, Michels M; Kaiser PK, Heier JS, Sy JP, Ianchulev T. Ranibizumab versus Verteporfin Photodynamic Therapy for Neovascular Age-Related Macular Degeneration: 2-Year Results of ANCHOR Study. Ophthalmology. 2009 Jan; 116(1) 57-65 PMID: 19118696.

Brown DM, Michels M, Kaiser PK, Heier JS, Sy JP, Ianchulev T; ANCHOR Study Group. Ranibizumab versus Verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study. Ophthalmology. 2009 Jan; 116(1):57-65. PMID: 19118696.

Smith SV, Benz MS, Brown DM. Cystoid Macular Edema due to Albumin-Bound Paclitaxel Therapy. Archives of Ophthalmology. 2008 Nov; 126:1605-6. PMID: 19001234.

Regillo CD, Brown DM, Abraham P, Kaiser PK, Mieler WF, Yue H, Ianchulev T, Schnieder S, Shams N. Randomized, Double-Masked, Sham-Controlled Trial of Ranibizumab for Neovascular Age-Related Macular Degeneration: PIER Study Year 1. American Journal Ophthalmology. 2008 Feb; 145:239-248. PMID: 18222192.

Kaiser PK, Brown DM, Zhang K, Hudson HL, Holz FG, Shapiro H, Schneider S, Acharya N. Ranibizumab for Predominantly Classic Neovascular Age-related Macular Degeneration: Subgroup Analysis of First-year ANCHOR Results. American Journal Ophthalmology. 2007 Dec; 144: 850-57. PMID: 17949673.

Brown DM, Regillo CD. Anti-VEGF agents in the treatment of neovascular age-related macular degeneration: applying clinical trial results to the treatment of everyday patients. American Journal Ophthalmology. 2007 Oct; 144(4):627-37. PMID: 17893015.

Diabetic Retinopathy Clinical Research Network, Browning DJ, Glassman AR, Aiello LP, Beck RW, Brown DM, Fong DS, Bressler NM, Danis RP, Kinyoun JL, Nguyen QD, Bhavsar AR, Gottlieb J, Pieramici DJ, Rauser ME, Apte RS, Lim JI, Miskala PH. Relationship between optical coherence tomography-measured central retinal thickness and visual acuity in diabetic macular edema. Ophthalmology. 2007 Mar; 114(3):525-36. PMID: 17123615.

Brown DM, Kaiser PK, Michels M, Soubrane G, Heier JS, Kim RY, Sy JP, Schneider S for the ANCHOR Study Group. Comparison of Ranibizumab and Verteporfin Photodynamic Therapy for Neovascular Age-Related Macular Degeneration: 1-Year Results of the ANCHOR Study. New England J Med. 2006 Oct 5; 355: (14) 1432-1444. PMID: 17021319.

Rosenfeld PJ, Brown DM, Heier JS, Boyer DS, Kaiser PK, Chung CY, Kim R for the MARINA Study Group. Ranibizumab for Neovascular Age-Related Macular Degeneration: 2-Year Results of the MARINA Study. New England J Med. 2006 Oct 5; 355: (14) 1419-1431. PMID: 17021318.

Brown DM, Beardsley R, Fish RH, Kim RY, Wong TP. Long Term Stability of Circumferential Silicone Sponge Scleral Buckling Elements. RETINA. 2006 Jul-Aug; 26: 645-49. PMID: 16829806

Brown DM, Graemiger RA, Hergersberg M, Schinzel A, Messmer EP, Niemeyer G, Schneeberger SA, Streb LM, Taylor CM, Kimura AE, Weingeist TA, Sheffield VC, Stone, EM. Genetic Linkage of Wagner Disease and Erosive Vitreoretinopathy. Archives of Ophthalmology. 1995 May; 113(5):671-5. PMID: 7748141.

Brown DM, Vandenburg K, Kimura AE, Weingeist TA, Sheffield VC, Stone EM. Frameshift mutations in the procollagen II gene in Stickler Syndrome. Human Molecular Genetics. 1995 Jan; 4(1):141-142. PMID: 7711727.

Brown DM, Sobol WG, Weingeist TA, Folk J. Retinal arteriolar macroaneurysms- Long Term Visual Outcome. British Journal of Ophthalmology. 1994 Jul; 78:534-38. PMID: 7918263

Boldt HC, Brown DM, McGeorge AJ. Echographic Diagnosis of Retinoschisis Facilitated by Scleral Indentation. American Journal Ophthalmology. 1994 Jul 15; 118:123-4. PMID: 8023868.

Brown DM, Weingeist TA, Kimura AE, Stone EM. Erosive vitreoretinopathy- A new clinical entity. Ophthalmology. 1994 Apr; 101 (4) 694-704. PMID: 8152765.

Brown DM, Nichols BE, Weingeist TA, Sheffield VC, Kimura AE, Stone EM. Procollagen II mutation in Stickler syndrome. Archives of Ophthalmology. 1992 Nov; 110:1589-93. PMID: 1444917.

Brown DM, Kimura AE, Ossoinig KC, Weiner GP. Leukemic optic nerve head infiltration treated with oral trans-retinoic acid. Ophthalmology. 1992 Sep; 99:1434-1437. PMID: 1407980.

Joos KM, Brown DM, Alward WL. A multilens case. Archives of Ophthalmology. 1991 Oct; 109:1343-1344. PMID: 1929910.

Brown DM, Boniuk M, Font R. Diffuse malignant melanoma of the iris with metastases. Survey of Ophthalmology. 1990 Mar-Apr; 34:357-364. PMID: 2183381.

Livesay JJ, Cooley DA, Montero CG, Warriam RK, Brown DM, JM Duncan. Surgical experience in descending thoracic aneurysmectomy with and without adjuncts to avoid ischemia. Annals of Thoracic Surgery. 1985 Jan; 39:37-46. PMID: 3966835

Publications (Journals)

Storey PP, Tauqeer Z, Yonekawa Y, Todorich B, Wolfe JD, Shah SP, Shah AR, Koto T, Abbey AM, Morizane Y, Sharma P, Wood EH, Morizane-Hosokawa M, Pendri P, Pancholy M, Harkey S, Jeng-Miller KW, Obeid A, Borkar DS, Chen E, Williams P, Okada AA, Inoue M, Shiraga F, Hirakata A, Shah CP, Prenner J, Garg S; for the; Post-Injection Endophthalmitis (PIE) Study Group. The Impact of Prefilled Syringes on Endophthalmitis following Intravitreal Injection of Ranibizumab. Am J Ophthalmol. 2018 Dec 12. pii: S0002-9394(18)30668-8.

Bressler SB, Beaulieu WT, Glassman AR, Gross JG, Melia M, Chen E, Pavlica MR, Jampol LM; Diabetic Retinopathy Clinical Research Network. Panretinal Photocoagulation Versus Ranibizumab for Proliferative Diabetic Retinopathy: Factors Associated with Vision and Edema Outcomes. Ophthalmology. 2018 Nov;125(11):1776-1783.

Derham AM, Chen E, Bunya VY, O’Malley RE. Bilateral Herpetic Keratitis After Bilateral Intravitreal Bevacizumab for Exudative Macular Degeneration. Cornea. 2017 Jul;36(7):878-879.

Khurana RN, Wykoff CC, Bansal AS, Akiyama K, Palmer JD, Chen E, Chang LK, Major JC Jr, Wu C, Wang R, Croft DE, Wong TP. The Association of Epiretinal Membrane with Macular Hole Formation After Rhegmatogenous Retinal Detachment Repair. Retina. 2017 Jun; 37(6):1073-1078.

Rayess N, Rahimy E, Shah CP, Wolfe JD, Chen E, DeCroos FC, Storey P, Garg SJ, Hsu J. Incidence and clinical features of post-injection endophthalmitis according to diagnosis. Br J Ophthalmol. 2016 Aug;100(8):1058-61.

Li AL, Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC Jr, Brown DM, Schefler AC, Kim RY, OʼMalley RE. Endophthalmitis After Intravitreal Injection: Role of Prophylactic Topical Ophthalmic Antibiotics. Retina. 2016 Jul;36(7):1349-56.

Rayess N, Rahimy E, Storey P, Shah CP, Wolfe JD, Chen E, DeCroos FC, Garg SJ, Hsu J. Post-injection endophthalmitis rates and characteristics following intravitreal bevacizumab, ranibizumab and aflibercept. Am J Ophthalmol. 2016 May;165:88-93.

Major JC, Wykoff CC, Mariani AF, Chen E, Croft DE, Brown DM. Comparison of spectral-domain and time-domain optical coherence tomography in the detection of neovascular age-related macular degeneration activity. Retina. 2014 Jan:34(1):48-54.

Wykoff CC, Brown DM, Chen E, Major JC, Croft DE, Mariani A, Wong TP, SAVE Study Group. SAVE (Super-dose anti-VEGF) trial: 2.0 mg ranibizumab for recalcitrant neovascular age related macular degeneration: 1-year results. Ophthalmic Surg Lasers Imaging Retina. 2013 Mar-Apr;44(2):121-6.

Brown DM, Chen E, Mariani AF, Major JC. The SAVE (Super-dose Anti-VEgf) Trial: 2.0mg Intravitreal Ranibizumab for Recalcitrant Neovascular Age-Related Macular Degeneration: Fixed Dose Primary Endpoint. Ophthalmology. 2013 Feb;120(2):349-54.

Collaborative Anti-VEGF Ocular Vascular Complications Group. Insight into 144 patients with ocular vascular events during VEGF antagonist injections. Clinical Ophthalmology. 2012:6:343-363.

Chen E, Lin MY, Cox J, Brown DM. Endophthalmitis after intravitreal injection: the importance of Viridans streptococci. Retina. 2011 Sep;31(8):1525-33.

Chen E, Benz MS, Fish RH, Brown DM, Wong TP, Kim RY, Major JC. Use of nepafenac (nevanac) in combination with intravitreal anti-VEGF agents in the treatment of recalcitrant exudative macular degeneration requiring monthly injections. Clinical Ophthalmology. 2010:4:1249-1252.

Chen E, Brown DM, Benz MS, Fish RH, Wong TP, Kim RY, Major JC. Spectral domain optical coherence tomography (sdOCT) as an effective screening test for hydroxychloroquine retinopathy (the “flying saucer” sign). Clinical Ophthalmology. 2010:4:1151-1158.

Chen E, Brown DM, Wong TP, Benz MS, Kegley E, Cox J, Fish RH, Kim RY. Lucentis® using visudyne® study: determining the threshold-dose fluence of verteporﬁn (visudyne®) photodynamic therapy (PDT) combined with intravitreal ranibizumab (lucentis®) for exudative macular degeneration. Clinical Ophthalmology. 2010:4:1073–1079.

Chen E, Ho AC, Garg SJ, Brown GC, Kaiser RS. Streptococcus mitis endophthalmitis presenting as frosted branch angiitis after intravitreal pegaptanib sodium injection. Ophthalmic Surg Lasers Imaging. 2009 Mar-Apr;40(2):192-4.

Chen E, Hsu J, Park CH. Acute vision loss following intravitreal bevacizumab for diabetic macular edema. Ophthalmic Surg Lasers Imaging. 2009 Jan-Feb;40(1):68-70.

Chen E. Relentless Placoid Chorioretinitis. Ophthalmic Surg Lasers Imaging. 2009 Jan-Feb;40(1):87-8.

Hsu J, Chen E, Gupta OP, Fineman MS, Garg SJ, Regillo CD. Hypotony after 25-Gauge vitrectomy using oblique versus direct cannula insertions in fluid-filled eyes. Retina. 2008 Jul-Aug;28(7):937-40.

Recchia FM, Chen E, Li C, Maguluri S. Use of COX-2 inhibitors in patients with retinal venous occlusive disease. Retina. 2008 Jan;28(1):134-137.

Hsu J, Chen E, Vander JF. Cytomegalovirus retinitis following intravitreal triamcinolone in an immunocompetent patient. Retinal Cases & Brief Reports. 1(4):208-210, Fall 2007.

Chen E. 25-Gauge transconjunctival sutureless vitrectomy. Curr Opin Ophthalmol. 2007 May; 18(3):188-93.

Chen E, Regillo CD. Retinal complications of cataract and refractive surgery. Retinal Physician. 2007 Apr; 4(3):28-32.

Chen E, Kaiser RS, Vander JF. Intravitreal bevacizumab for refractory pigment epithelial detachment with occult choroidal neovascularization in age-related macular degeneration. Retina. 2007 Apr-May; 27(4):445-50.

Chen E. Comment on "Cognitive Impairment in the Age-Related Eye Disease Study." Evidence-Based Ophthalmology. 2006 Oct 7(4):212-3.

Chen E, Park CH. Use of intravitreal bevacizumab as a preoperative adjunct for tractional retinal detachment repair in severe proliferative diabetic retinopathy. Retina. 2006 Jul-Aug; 26(6):699-700.

Chen E, Morrison DG, Donahue SP. Acute myeloid leukemia presenting as bilateral proptosis from diffuse extraocular muscle infiltration. Am J Ophthalmol. 2004 May;137(5):948-50.

Rupnow BA, Murtha AD, Chen E, Knox SJ. Myc activation reduces fibroblast clonogenicity via an apoptotic mechanism that can be suppressed by a soluble paracrine factor. Cancer Letters; 1998 May 15, 127(1-2):211-9.

Knox SJ, Varghese A, Khan W, Chen E, MacManus M, Ray G, Lee K, Lamborn KR. A prospective study of radiation therapy-associated thrombocytopenia. Blood; 1997 Nov 15, 90(10):4237-8.

Publications (Clinical Trial Papers)

Diabetic Retinopathy Clinical Research Network. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology. 2010 June;117(6):1064-1077.e35

OZURDEX GENEVA Study Group. Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion. Ophthalmology. 2010 Jun;117(6):1134-1146.e3.

SCORE Study Research Group. SCORE Study Report 7: incidence of intravitreal silicone oil droplets associated with staked-on vs luer cone syringe design. Am J Ophthalmol. 2009 Nov;148(5):725-732.e7.

SCORE Study Research Group. A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular Edema secondary to branch retinal vein occlusion: the Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study report 6. Arch Ophthalmol. 2009 Sep;127(9):1115-28.

Diabetic Retinopathy Clinical Research Network. Optical coherence tomography measurements and analysis methods in optical coherence tomography studies of diabetic macular edema. Ophthalmology. 2008 Aug;115(8):1366-71, 1371.e1.

Fish RH, Morris RE, Witherspoon CD, Kimble JA No Light Perception: Prognostic Significance in Acute Ocular Trauma. Surgical Forum, 39: 512 - 514, 1988

Fish RH, Kline LB, Hanumanthu VK, et al. Hysterical Bitemporal Hemianopia “Cured” With Contact Lenses. J. Clin. Neuro-ophth. 10: 76 - 78, 1990

Fish RH, Hogan RN, Nightingale SD, Anand R Peripapillary Angiomatosis Associated with Cat Scratch Neuroretinitis. Arch. Ophthalmol. 110: 323, 1992

Rabb MF, Jampol LM, Fish RH, et al. Retinal Periphlebitis in Patients with Acquired Immunodeficiency Syndrome With Cytomegalovirus Retinitis Mimics Acute Frosted Retinal Periphlebitis. Arch. Ophthalmol., 110: 1257 - 1260, 1992

Nemeth GG, Fish RH, Itani KM, Yates BE Hansen’s Disease. Arch. Ophthalmol., 110: 1482 - 1483; 1992

Fish RH, Anand R, Izbrand DS Macular Pseudoholes: Clinical Features and Accuracy of Diagnosis. Ophthalmology, 99: 1665 - 1670, 1992

Anand R, Nightingale SD, Fish RH, Smith TJ, Ashton P Control of Cytomegalovirus Retinitis Using Sustained Release of Intraocular Ganciclovir. Arch.Ophthalmol., 111: 223 - 227, 1993

Fish RH, Territo C, Anand R Pseudohypopyon in Unilateral Acute Idiopathic Maculopathy. Retina, 13: 26 - 28, 1993

Anand R, Font RL, Fish RH, Nightingale SD. Pathology of Cytomegalovirus Retinitis Treated with Sustained Release Intravitreal Ganciclovir. Ophthalmology, 100: 1032 - 1039, 1993.

Fish RH, Hoskins JC, Kline LB. Toxoplasmosis Neuroretinitis. Ophthalmology, 100: 1177 - 1182, 1993.

Ganciclovir Implant Study Group. Treatment of Cytomegalovirus Retinitis with a Sustained-Release Ganciclovir Implant. N. Eng. J. Med., 337: 83 - 90, 1997.

The Vitravene Study Group. Randomized Dose-comparison Studies of Intravitreal Fomivirsen for Treatment of Cytomegalovirus Retinitis That Has Reactivated or is Persistently Active Despite Other Therapies in Patients with AIDS. Am. J. Ophthalmol., 133: 475-483, 2002.

The Vitravene Study Group. Safety of Intravitreous Fomivirsen for Treatment of Cytomegalovirus Retinitis in Patients with AIDS. Am J. Ophthalmol., 133: 484- 498, 2002.

Brown DM, Beardsley R, Fish RH, Kim RY, Wong TP. Long Term Stability of Circumferential Silicone Sponge Scleral Buckling Elements. Retina, 26: 645-49, 2005.

Luviano DM, Benz MS, Kim RY, Fish RH, Wong TP, Kegley EN, Brown DM. .Selected clinical comparisons of spectral domain and time domain optical coherence tomography. Ophthalmic Surg Lasers Imaging, 40:325-8, 2009.

Chen E, Benz MS, Fish RH, Brown DM, Wong TP, Kim RY, Major JC. Use of nepafenac (nevanac) in combination with intravitreal anti-VEGF agents in the treatment of recalcitrant exudative macular degeneration requiring monthly injections. Clinical Ophthalmology. 2010:4:1249-1252.

Chen E, Brown DM, Benz MS, Fish RH, Wong TP, Kim RY, Major JC. Spectral domain optical coherence tomography (sdOCT) as an effective screening test for hydroxychloroquine retinopathy (the “flying saucer” sign). Clinical Ophthalmology. 2010:4:1151-1158.

Chen E, Brown DM, Wong TP, Benz MS, Kegley E, Cox J, Fish RH, Kim RY. Lucentis® using visudyne® study: determining the threshold-dose fluence of verteporﬁn (visudyne®) photodynamic therapy (PDT) combined with intravitreal ranibizumab (lucentis®) for exudative macular degeneration. Clinical Ophthalmology. 2010:4:1073–1079.

Frick KD, Drye LT, Kempen JH, Dunn JP, Holland GN, Latkany P, Rao NA, Sen HN, Sugar EA, Thorne JE, Wang RC, Holbrook JT; Multicenter Uveitis Steroid Treatment-MUST Trial Research Group. Associations among visual acuity and vision and health-related quality of life among patients in the multicenter uveitis steroid treatment trial. Invest Ophthalmol Vis Sci. 2012 Mar 9;53(3):1169-76.

Sen HN, Drye LT, Goldstein DA, Larson TA, Merrill PT, Pavan PR, Sheppard JD, Burke A, Srivastava SK, Jabs DA; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Hypotony in patients with uveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial. Ocul Immunol Inflamm. 2012 Apr;20(2):104-12.

Friedman DS, Holbrook JT, Ansari H, Alexander J, Burke A, Reed SB, Katz J, Thorne JE, Lightman SL, Kempen JH; MUST Research Group. Risk of elevated intraocular pressure and glaucoma in patients with uveitis: results of the multicenter uveitis steroid treatment trial. Ophthalmology. 2013 Aug;120(8):1571-9.

Danis RP, Domalpally A, Chew EY, Clemons TE, Armstrong J, SanGiovanni JP, Ferris FL 3rd; AREDS2 Study Group. Methods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 Report Number 2). Invest Ophthalmol Vis Sci. 2013 Jul 8;54(7):4548-54.

Kempen JH, Sugar EA, Jaffe GJ, Acharya NR, Dunn JP, Elner SG, Lightman SL, Thorne JE, Vitale AT, Altaweel MM; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema. Ophthalmology. 2013 Sep;120(9):1852-9.

Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Sugar EA, Holbrook JT, Kempen JH, Burke AE, Drye LT, Thorne JE, Louis TA, Jabs DA, Altaweel MM, Frick KD. Cost-effectiveness of fluocinolone acetonide implant versus systemic therapy for noninfectious intermediate, posterior, and panuveitis. Ophthalmology. 2014 Oct;121(10):1855-62.

Diabetic Retinopathy Clinical Research Network, Wells JA, Glassman AR, Ayala AR, Jampol LM, Aiello LP, Antoszyk AN, Arnold-Bush B, Baker CW, Bressler NM, Browning DJ, Elman MJ, Ferris FL, Friedman SM, Melia M, Pieramici DJ, Sun JK, Beck RW. Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema. N Engl J Med. 2015 Mar 26;372(13):1193-203.

Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Kempen JH, Altaweel MM, Drye LT, Holbrook JT, Jabs DA, Sugar EA, Thorne JE. Benefits of Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study. Ophthalmology. 2015 Oct;122(10):1967-75.

Multicenter Uveitis Steroid Treatment (MUST) Trial Follow-up Study Research Group. Quality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment Trial and Follow-up Study. Ophthalmology. 2015 Oct;122(10):1976-86.

Tomkins-Netzer O, Lightman S, Drye L, Kempen J, Holland GN, Rao NA, Stawell RJ, Vitale A, Jabs DA; Multicenter Uveitis Steroid Treatment Trial Research Group. Outcome of Treatment of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial 2-Year Results. Ophthalmology. 2015 Nov;122(11):2351-9.

Kempen JH, Van Natta ML, Altaweel MM, Dunn JP, Jabs DA, Lightman SL, Thorne JE, Holbrook JT; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Factors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial. Am J Ophthalmol. 2015 Dec;160(6):1133-1141.e9.

Wykoff CC, Croft DE, Brown DM, Wang R, Payne JF, Clark L, Abdelfattah NS, Sadda SR; TREX-AMD Study Group. Prospective Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: TREX-AMD 1-Year Results. Ophthalmology. 2015 Dec;122(12):2514-22.

Wang R, Wykoff CC, Christie L, Croft DE, Major JC Jr, Fish RH, Brown DM. CHOROIDAL NEOVASCULARIZATION SECONDARY TO ALEXANDRITE LASER EXPOSURE. Retin Cases Brief Rep. 2016 Summer;10(3):244-8.

Wells JA, Glassman AR, Jampol LM, Aiello LP, Antoszyk AN, Baker CW, Bressler NM, Browning DJ, Connor CG, Elman MJ, Ferris FL, Friedman SM, Melia M, Pieramici DJ, Sun JK, Beck RW; Diabetic Retinopathy Clinical Research Network. Association of Baseline Visual Acuity and Retinal Thickness With 1-Year Efficacy of Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema. JAMA Ophthalmol. 2016 Feb;134(2):127-34.

Li AL, Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC Jr, Brown DM, Schefler AC, Kim RY, OʼMalley RE. ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION: Role of Prophylactic Topical Ophthalmic Antibiotics. Retina. 2016 Jul;36(7):1349-56.

AREDS2 Research Group, Al-Holou SN, Tucker WR, Agrón E, Clemons TE, Sperduto RD, Ferris FL 3rd, Chew EY. The Association of Statin Use with Cataract Progression and Cataract Surgery: The AREDS2 Report Number 8. Ophthalmology. 2016 Apr;123(4):916-7.

Holbrook JT, Sugar EA, Burke AE, Vitale AT, Thorne JE, Davis JL, Jabs DA; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Dissociations of the Fluocinolone Acetonide Implant: The Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study. Am J Ophthalmol. 2016 Apr;164:29-36.

Abdelfattah NS, Al-Sheikh M, Pitetta S, Mousa A, Sadda SR, Wykoff CC; Treat-and-Extend Age-Related Macular Degeneration Study Group. Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial. Ophthalmology. 2017 Feb;124(2):215-223.

Jampol LM, Glassman AR, Liu D, Aiello LP, Bressler NM, Duh EJ, Quaggin S, Wells JA, Wykoff CC; Diabetic Retinopathy Clinical Research Network. Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema.Ophthalmology. 2018 Jul;125(7):1054-1063.

Payne JF, Clark WL, Bruce BB, Wykoff CC, Brown DM, Menke BM, Iverson SM, Allen KF, Boyer DS; Treat & Extend Protocol in Patients with Diabetic Macular Edema Study Group. Retinopathy Regression with Treat and Extend Ranibizumab for Diabetic Macular Edema. Ophthalmology. 2018 Aug;125(8):1304-1306.

Abdelfattah NS, Hariri AH, Al-Sheikh M, Pitetta S, Ebraheem A, Wykoff CC, Sadda SR; TREX-AMD Study Group. Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial. Am J Ophthalmol. 2018 Aug;192:84-90.

Keenan TD, Agrón E, Domalpally A, Clemons TE, van Asten F, Wong WT, Danis RG, Sadda S, Rosenfeld PJ, Klein ML, Ratnapriya R, Swaroop A, Ferris FL 3rd, Chew EY; AREDS2 Research Group. Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16. Ophthalmology. 2018 Dec;125(12):1913-1928.

Yu JJ, Agrón E, Clemons TE, Domalpally A, van Asten F, Keenan TD, Cukras C, Chew EY; Age-Related Eye Disease Study 2 Research Group. Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17. Ophthalmology. 2019 Feb;126(2):261-273.

Oliver GF, Stathis RM, Furtado JM, Arantes TE, McCluskey PJ, Matthews JM, International Ocular Syphilis Study Group, Smith JR. Current ophthalmology practice patterns for syphilitic uveitis. Br J Ophthalmol 2019 [In press]

Patel NA, Shah P, Yanuzzi NA, Ansari Z, Zaveri JS, Relhan N, Williams BK, Kuriyan AE, Henry CR, Sridhar J, Haddock L, Fortun JA, Albini TA, Davis JL, Flynn HW Jr. Clinical outcomes of 4-point scleral fixated 1-piece hydrophobic acrylic equiconvex intraocular lens using polytetrafluoroethylene suture. Clin Ophthalmol 2018;12:2145-2148.

Henry CR, Becker MD, Yang Y, Davis JL. Pars plana vitrectomy for the treatment of uveitis. Am J Ophthalmol 2018;190:142-149.

Yang YS, Zhang L, Asdaghi N, Henry CR, Davis JL. Acute macular neuroretinopathy in Susac syndrome: a new association. Retin Cases Brief Rep 2018 [Epub ahead of print].

Henry TD, Henry CR. The importance of vision. Catheter Cardiovasc Interv 2017;90:10-11.

Henry CR, Al-Attar L, Cruz-Chacon AM, Davis JL. Chorioretinal lesions presumed secondary to zika virus infection in an immunocompromised adult. JAMA Ophthalmol. 2017;135:386-389.

Palioura S, Henry CR, Amescua GA, Alfonso EC. Role of steroids in the treatment of bacterial keratitis. Clin Ophthalmol 2016;10:179-186.

Henry CR, Sisk RA, Tzu JH, Albini TA, Davis JL, Murray TG, Berrocal AM. Long-term follow-up of intravitreal bevacizumab for the treatment of pediatric retinal and choroidal diseases. J AAPOS 2015;19:541-548.

Reddy AK, Gonzalez MA, Henry CR, Yeh S, Sobrin L, Albini TA. Diagnostic sensitivity of indocyanine green angiography for birdshot chorioretinopathy. JAMA Ophthalmol 2015;133:840-843.

Erickson BP, Henry C, Alabiad CR. Recurrent dermatofibrosarcoma protuberans masquerading as a lacrimal sac neoplasm: a case report and review. Ophthal Plast Reconstr Surg 2015;31:e135-138.

Henry CR, Smiddy WE, Flynn HW Jr. Author Reply. Retina 2014;34:e42.

Henry CR, Schwartz SG, Flynn Jr. HW. Endophthalmitis following pars plana vitrectomy for vitreous floaters. Clin Ophthalmol 2014;8:1649-1653.

Henry CR, Smiddy WE, Flynn Jr. HW. Pars plana vitrectomy for vitreous floaters: is there such a thing as minimally invasive vitreoretinal surgery? Retina 2014;34:1043-1045.

Ashkenazy N, Henry CR, Abbey AM, McKeown CA, Berrocal AM, Murray TG. Successful treatment of juvenile xanthogranuloma using bevacizumab. J AAPOS 2014;18:295-297.

Singh RS, Covert DJ, Henry CR, Bhatia SK, Croskey J, Sanchez CR, Han DP. Retinal complications associated with pars plana vitrectomy for macular holes or epiretinal membranes in eyes with previous retinal detachment repair. JAMA Ophthalmol 2014;132:118-119.

Henry CR, Flynn Jr. HW. Keratitis-induced endophthalmitis: author reply. Ophthalmology 2013;120:e49-50.

Henry CR, Flynn Jr. HW, Miller D, Schefler AC, Forster RK, Alfonso EC. Delayed-onset endophthalmitis associated with corneal suture infections. J Ophthalmic Inflamm Infect 2013:3:51.

Henry CR, Hodapp E, Hess DJ, Blieden LS, Berrocal AM. Fluorescein angiography findings in phacomatosis pigmentovascularis. Ophthalmic Surg Lasers Imaging Retina 2013;44:201-203.

Henry CR, Flynn Jr. HW, Miller D, Forster RK, Alfonso EC. Infectious keratitis progressing to endophthalmitis: a 15-year study of microbiology, associated factors, and clinical outcomes. Ophthalmology 2012;119:2443-2449.

Henry CR, Berrocal AM, Hess DJ, Murray TG. Intraoperative spectral-domain optical coherence tomography in Coats’ disease. Ophthalmic Surg Lasers Imaging 2012;43:e80-84.

Henry CR, Canto AP, Galor A, Yoo SH. Epithelial ingrowth under LASIK flap: clinical characteristics, risk factors, and visual outcomes in patients requiring flap lift. J Refract Surg 2012;28:488-492.

Covert DJ, Henry CR, Bhatia SK, Croskrey J, Sanchez CR, Han DP. Intraoperative retinal cannulated vitrectomy systems compared to the standard twenty-gauge system. Arch Ophthalmol 2012;130:186-189.

Covert DJ, Henry CR, Koenig SB. Intraocular lens power selection in the second eye of patients undergoing bilateral, sequential cataract extraction. Ophthalmology 2010;117:49-54.

Covert DJ, Henry CR, Sheth BP. Well-tolerated intracorneal wood foreign body of forty-years duration. Cornea 2009;28:597-598.

Henry TD, Sharkey SW, Burke N, Chavez IJ, Graham KJ, Henry CR, et al. A regional system to provide timely access to percutaneous coronary intervention for ST-elevation myocardial infarction. Circulation 2007;116:721-728.

Henry CR, Satran D, Lindgren B, Adkinson C, Henry TD. Carbon monoxide poisoning, myocardial injury, and mortality – reply. JAMA 2006;295:2602.

Henry CR, Satran D, Lindgren B, Adkinson CD, Nicholson CI, Henry TD. Myocardial injury and long-term mortality following moderate to severe carbon monoxide poisoning. JAMA 2006;295:398-402.

Newell MC, Henry CR, Sigakis CJG, Unger BT, Larson DM, Chavez IJ, Burke MN, Traverse JH, Henry TD. Comparison of safety and efficacy of sirolimus-eluting stents versus bare metal stents in patients with ST-segment elevation myocardial infarction. Am J Cardiol 2006;97:1299-1302.

Satran D, Henry CR, Henry TD. Response to letter to the editor re: cardiovascular manifestations of carbon monoxide poisoning. J Am Coll Cardiol 2006;47:691.

Satran D, Henry CR, Adkinson C, Chaney CI, Bracha Y, Henry TD. Cardiovascular manifestations of moderate to severe carbon monoxide poisoning. J Am Coll Cardiol 2005;45:1513-1516.

Satran A, Bart BA, Henry CR, Murad MB, Talukdar S, Satran D, Henry TD. Increased prevalence of coronary artery aneurysms among cocaine users. Circulation 2005;111:2424-2429.

Kim Ry, Yao XY, Marmor MF. Oxygen dependency of retinal adhesion. Invest Ophthal Vis Sci. 1993; 34: 2074-2078.

Kim Ry, Hu LK, Foster BS Gragoudas ES, Young LHY. Photodynamic therapy of pigmented choroidal melanoma of >3-mm thickness. Ophthalmology 1996; 103: 2029-36.

Kuroki M, Voest EE, Amano S, Beerepoot LV, Takashima S, Tolentino M, Kim Ry, Rohan RM, Colby KA, Yeo KT, Adamis AP. Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo. J Clin Invest. 1996; 98: 1667-75.

Chon C, Yao XY, Dalal R, Takeuchi A, Kim Ry, Marmor MF. An experimental model of retinal pigment epithelial and neurosensory serous detachment. Retina 1996; 16: 139-144.

Young LHY, Howard MA, Hu LK, Kim Ry, Gragoudas ES. Photodynamic therapy of pigmented choroidal melanoma using a liposomal preparation of benzoporphyrin derivative. Arch Ophthalmol 1996; 114: 186-192.

Kim Ry, Cooper KL, Kelly LD. Predictive factors for response to medical therapy in bacterial ulcerative keratitis. Graefes Arch Clin Exp Ophthalmol. 1996; 234: 731-8.

Kim Ry, Hu LK, Flotte TJ, Gragoudas ES, Young LHY. Digital angiography of experimental choroidal melanoma using benzoporphyrin derivative-monoacid. Am J Ophthalmol. 1997; 123: 810-816.

Kim Ry and Loewenstein JI. Systemic diseases manifesting as exudative retinal detachment. International Ophthalmology Clinics.1998; 38:177-195

Kim Ry and Young LHY. Use of Photodynamic Therapy for Treatment of Ocular Malignancies. Ophthalmology Clinics of North America. 1999; 12:167-176.

Kim Ry and D’Amico DJ. Post-operative complications of pneumatic retinopexy. International Ophthalmology Clinics. 2000; 40:165-173.

Kim Ry and Young LHY. Bone marrow transplant retinopathy. In: Jakobiec FA and Albert DM, eds. Principles and practice of ophthalmology. 2nd ed. Philadelphia: W. B. Saunders; 2000. p. 2236-2240.

Kim Ry and Dana MR. Graft versus host disease. In: Jakobiec FA and Albert DM, eds. Principles and Practice of Ophthalmology. 2nd ed. Philadelphia: W. B. Saunders 2000. p. 4994-5001.

Lit ES, Kim Ry, D’Amico DJ. Surgical removal of subfoveal choroidal neovascularization without removal of posterior hyaloid: a consecutive series in young patients. Retina. 2001; 21: 317-323.

Kim Ry Anderlini P, Naderi AA, Rivera P, Ahmadi MA, Esmaeli B. Scerlitis as the initial clinical manifestation of graft-versus-host disease after allogenic bone marrow transplantion. Am J Ophthalmol. 2002; 133: 843-845.

Kim Ry, Gragoudas EG, Young LHY. Future laser approaches in treatment of ocular melanomas. International Ophthalmology Clinics 46: (1) 27-39, 2006

Brown DM, Kaiser PK, Michels M, Soubrane G, Heier JS, Kim Ry, Sy JP, Schneider S for the ANCHOR Study Group. Comparison of Ranibizumab and Verteporfin Photodynamic Therapy for Neovascular Age-Related Macular Degeneration: 1-Year Results of the ANCHOR Study. New Eng J Med, 355: (14) 1432-1444, 2006.

Brown DM, Beardsley RM, Fish RH, Wong TP, Kim Ry. Long-term stability of circumferential silicone sponge scleral buckling exoplants. Retina. 2006 Jul-Aug;26(6):645-9.

Kim Ry, Gragroudas ES, Young LH. Future laser approaches in melanoma treatment. Int Ophthalmol Clin. 2006 Winter;46(1):27-39.

Luviano DM, Benz MS, Kim Ry, Fish RH, Wong TP, Kegley EN, Brown DM. Selected clinical comparisons of spectral domain and time domain optical coherence tomography. Ophthalmic Surg Lasers Imaging. 2009 May-Jun;40(3):325-8

Multicenter Uveitis Steroid Treatment Trial Research Group. The Multicenter Uveitis Steroid Treatment (MUST) Trial: Rationale, Design and Baseline Characteristics. Am J Ophthalmol 2010; 149:550-561. e10. Epub 2010 Jan 25.

Chen E, Benz MS, Fish RH, Brown DM, Wong TP, Kim Ry, Major JC. Use of nepafenac (Nevanac) in combination with intravitreal anti-VEGF agents in the treatment of recalcitrant exudative macular degeneration requiring monthly injections. Clin Ophthalmol. 2010 Oct 28;4:1249-52.

Chen E, Brown DM, Benz MS, Fish RH, Wong TP, Kim Ry, Major JC. Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy (the "flying saucer" sign). Clin Ophthalmol. 2010 Oct 21;4:1151-8.

Chen E, Brown DM, Wong TP, Benz MS, Kegley E, Cox J, Fish RH, Kim Ry. Lucentis using Visudyne study: determining the threshold-dose fluence of verteporfin photodynamic therapy combined with intravitreal ranibizumab for exudative macular degeneration. Clin Ophthalmol. 2010 Oct 5;4:1073-9.

Hueber W, Patel DD, Dryja T, Wright AM, Koroleva I, Bruin G, Antoni C, Draelos Z, Gold MH; Psoriasis Study Group, Durez P, Tak PP, Gomez-Reino JJ; Rheumatoid Arthritis Study Group, Foster CS, Kim Ry, Samson CM, Falk NS, Chu DS, Callanan D, Nguyen QD; Uveitis Study Group, Rose K, Haider A, Di Padova F. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med. 2010 Oct 6;2(52):52ra72.

Gangaputra S, Altaweel MM, Foster CS, Friedman DS, Kim Ry, Rao PK, Reed S, Srivastava SK, Wong IG, Kempen JH. Morphologic assessment for glaucoma in the Multicenter Uveitis Steroid Treatment (MUST) Trial. Ocul Immunol Inflamm 2011;19(4):267-274.

The Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group; Writing Committee: Kempen JH, Altaweel MM, Holbrook JT, Jabs DA, Louis TA, Sugar EA, Thorne JE. Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: The Multicenter Uveitis Steroid Treatment Trial. Ophthalmology 2011;118(10):1916-1926.

Sugar EA, Jabs DA, Altaweel MM, Lightman S, Acharya N, Vitale AT, Thorne JE, for the Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Identifying a clinically meaningful threshold for change in uveitic macular edema evaluated by optical coherence tomography. Am J Ophthalmol 2011;152(6):1044-1052.

Sen HN, Drye LT, Goldstein DA, Larson TA, Merrill PT, Pavan PR, Sheppard JD, Burke A, Srivastava SK, Jabs DA, for the Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Hypotony in patients with uveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial. Ocul Immunol Inflamm 2012;20(2):104-12.

Frick KD, Drye LT, Kempen JH, Dunn JP, Holland GN, Latkany P, Rao NA, Sen HN, Sugar EA, Thorne JE, Wang RC, Holbrook JT, for the Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Associations among visual acuity and vision- and health-related quality of life among patients in the multicenter uveitis steroid treatment trial. Invest Ophthalmol Vis Sci 2012;53(3):1169-76.

Taylor SR, Lightman SL, Sugar EA, Jaffe GJ, Freeman WR, Altaweel MM, Kozak I, Holbrook JT, Jabs DA, Kempen JH, for the Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. The impact of macular edema on visual function in intermediate, posterior, and panuveitis. Ocul Immunol Inflamm 2012;20(3):171-81.

Domalpally A, Altaweel MM, Kempen JH, Myers D, Davis JL, Foster CS, Latkany P, Srivastava SK, Stawell RJ, Holbrook JT; MUST Trial Research Group. Optical coherence tomography evaluation in the Multicenter Uveitis Steroid Treatment (MUST) trial. Ocul Immunol Inflamm 2012;20(6):443-7.

Friedman DS, Holbrook JT, Katz J, Ansari H, Alexander J, Burke A, Prusakowski N, Reed S, Thorne JE, Kempen JH, for the Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Risk of elevated intraocular pressure and glaucoma in patients with uveitis; results of the Multicenter Uveitis Steroid Treatment Trial. Ophthalmology 2013;120(8):1571-9.

Kempen JH, Sugar EA, Acharya N, Altaweel MM, Dunn JP, Elner SG, Jaffe GJ, Lightman SL, Thorne JE, Vitale AT, for the Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Fluorescein angiography vs. optical coherence tomography for diagnosis of uveitic macular edema. Ophthalmology 2013;120(9):1852-9.

The Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group Writing Committee: Sugar EA, Holbrook JT, Kempen JH, Burke AE, Drye LT, Thorne JE, Louis TA, Jabs DA, Altaweel MA, Frick KD. Cost-Effectiveness of Fluocinolone Acetonide Implant versus Systemic Therapy for Noninfectious Intermediate, Posterior, and Panuveitis. Ophthalmology 2014;121(10):1855-62.

Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, Kempen JH, Altaweel MM, Drye LT, Holbrook JT, Jabs DA, Sugar EA, Thorne JE. Benefits of Systemic Anti-inflammatory Therapy Versus Fluocinolone Acetonide Intraocular Implant for Intermediate, Posterior and Panuveitis: 54 month results of The Multicenter Uveitis Steroid Treatment Trial (MUST) and Follow-up Study. Ophthalmology 2015;122(10):1967-75.

Kempen JH, Van Natta ML, Altaweel MM, Dunn JP, Jabs DA, Lightman SL, Thorne JE, Holbrook
JT, The Multicenter Uveitis Steroid Treatment Trial Research Group. Factors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial. Am J Ophthalmol 2015; 160(6):1133-1141

Sen HN, Abreu FM, Louis TA, Sugar EA, Altaweel MM, Elner SG, Holbrook JT, Jabs DA, Kim Ry, Kempen JH; Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study Research Group. Cataract Surgery Outcomes in Uveitis: The Multicenter Uveitis Steroid Treatment Trial. Ophthalmology 2016;123(1):183-90.

Wells JA, Glassman AR, Jampol LM, Aiello LP, Antoszyk AN, Baker CW, Bressler NM, Browning DJ, Connor CG, Elman MJ, Ferris FL, Friedman SM, Melia M, Pieramici DJ, Sun JK, Beck RW; Diabetic Retinopathy Clinical Research Network. Association of Baseline Visual Acuity and Retinal Thickness With 1-Year Efficacy of Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema. JAMA Ophthalmol. 2016 Feb;134(2):127-34

Li AL, Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC Jr, Brown DM, Schefler AC, Kim Ry, OʼMalley RE. ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION: Role of Prophylactic Topical Ophthalmic Antibiotics. Retina. 2016 Jul;36(7):1349-56.

Altaweel MM, Gangaputra SS, Thorne JE, Dunn JP, Elner SG, Jaffe GJ, Kim Ry, Rao PK, Reed SB, Kempen JH; MUST Research Group. Morphological assessment of the retina in uveitis. J Ophthalmic Inflamm Infect. 2016 Dec;6(1):33.

Abdelfattah NS, Al-Sheikh M, Pitetta S, Mousa A, Sadda SR, Wykoff CC; Treat-and-Extend Age-Related Macular Degeneration Study Group. Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial. Ophthalmology. 2017 Feb;124(2):215-223.

Writing Committee for the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study Research Group, Kempen JH, Altaweel MM, Holbrook JT, Sugar EA, Thorne JE, Jabs DA. Association Between Long-Lasting Intravitreous Fluocinolone Acetonide Implant vs Systemic Anti-inflammatory Therapy and Visual Acuity at 7 Years Among Patients With Intermediate, Posterior, or Panuveitis. JAMA. 2017 May 16;317(19):1993-2005.

Brown DM, Ou WC, Wong TP, Kim Ry, Croft DE, Wykoff CC; DAVE Study Group. Targeted Retinal Photocoagulation for Diabetic Macular Edema with Peripheral Retinal Nonperfusion: Three-Year Randomized DAVE Trial. Ophthalmology. 2018 May;125(5):683-690.

Jampol LM, Glassman AR, Liu D, Aiello LP, Bressler NM, Duh EJ, Quaggin S, Wells JA, Wykoff CC; Diabetic Retinopathy Clinical Research Network. Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema. Ophthalmology. 2018 Jul;125(7):1054-1063.

Yu JJ, Agrón E, Clemons TE, Domalpally A, van Asten F, Keenan TD, Cukras C, Chew EY; Age-Related Eye Disease Study 2 Research Group. Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17. Ophthalmology. 2018 Aug 22. pii: S0161-6420(18)31752-4.

Altaweel MM, Gangaputra SS, Dunn JP, Elner SG, Jaffe GJ, Kim Ry, Rao PK, Thorne JE, Kempen JH. Morphological assessment of fundus color images for the Multicenter Uveitis Steroid Treatment (MUST) Trial. Accepted by J Ophthalmic Inflamm Infect.

Lim LL, Sugar EA, Holbrook JT, Altaweel MM, Davis JL, Elner SG, Kempen JH, Kim Ry, Rao PK, Burke A, Stawell RJ. Retinal complications resulting in vision loss in the Multicenter Uveitis Steroid Treatment (MUST) Trial. In Preparation.

Journal Articles

Major Jr JC, Shah AR, Wong TP, Wykoff, CC, Lampen SIR, Ou WC, Brown DM. The Texas Taco Technique for Inverted Internal Limiting Membrane Flap in Large Full Thickness Macular Holes: A Short Term Pilot Study. Retina Submitted. 2018.
Lee IT, Lampen SI, Wong TP, Major Jr JC, Wykoff CC. Fovea-Sparing Rhegmatogenous Retinal Detachments: Impact of Clinical Factors on Surgical Outcomes. Ophthalmology Retina. Submitted. 2018.

Major JC Jr. Supreme Sight: Visual Adaptations in Raptors. HawkChalk: The Journal of the North American Falconer’s Association (NAFA) April 2017.

Li AL, Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC Jr, Brown DM, Schefler AC, Kim RY, OʼMalley RE. Endophthalmitis after intravitreal injection: role of prophylactic topical ophthalmic antibiotics. Retina 2016 Jul;36(7):1349-56.

Phillis CA, Bourke RD, Major JC. Diagnostic and Therapeutic Challenges. Retina 2016 Jun:36(6):1234-6.

Wang R, Wykoff CC, Christie L, Croft DE, Major JC Jr, Fish RH, Brown DM. Choroidal neovascularization secondary to alexandrite laser exposure. Retina Cases Brief Rep. 2016 Summer;10(3):244-8.

JC Major Jr, CC Wykoff, DE Croft, R Wang, AF Mariani, AE Lehmann, DM Brown. 2015. Aflibercept for pigment epithelial detachment for previously treated neovascular age-related macular degeneration. Can J Ophtho Oct 2015; 50(5):373-377.

Diabetic Retinopathy Clinical Research Network, Wells JA, Glassman AR, Ayala AR, Jampol LM, Aiello LP, Antoszyk AN, Arnold-Bush B, Baker CW, Bressler NM, Browning DJ, Elman MJ, Ferris FL, Friedman SM, Melia M, Pieramici DJ, Sun JK, Beck RW. Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema. N Engl J Med. 2015 Mar 26;372(13):1193-203.

CC Wykoff, DM Brown, DE Croft, JC Major Jr, TP Wong. 2015. Progressive retinal nonperfusion in ischemic central retinal vein occlusion. Retina Jan 2015; 35(1);43-47.

A Bedgood, SE Rand, JC Major Jr. 2015. Occult Retinal Detachment After Mild Traumatic Brain Injury: Case Report and Literature Review. Clin J Sport Med. Jan 25(1): 26-27.

JC Major Jr, CC Wykoff, AF Mariani, E Chen, DE Croft, & DM Brown. Comparison of spectral-domain and time-domain optical coherence tomography in the detection of neovascular age-related macular degeneration activity. Retina 2014 Jan; 34(1):48-54.

Major JC Jr, Hariprasad SM. Current concepts in managing wet AMD suboptimally responsive to anti-VEGF therapy. Ophthalmic Surg Lasers Imaging Retina. 2013 May-Jun; 44 (3):225-6.

JC Major Jr, Mariani AF, Benz MS, Brown DM. Purtscher’s-like Retinopathy Associated with Pempighus Vulgaris. Retinal Cases & Brief Reports Fall 2013 - Volume 7 - Issue 4 - p 304-306.

CC Wykoff, DM Brown, E Chen, JC Major Jr, DE Croft, A Mariani, TP Wong; SAVE Study Group. SAVE (Super-dose anti-VEGF) trial: 2.0 mg ranibizumab for recalcitrant neovascular age-related macular degeneration: 1-year results. Ophthalmic Surg Lasers Imaging Retina. 2013 Mar-Apr; 44 (2):121-6.

DM Brown, E Chen, A Mariani, JC Major Jr, SAVE Study Group. Super-dose anti-VEGF (SAVE) trial: 2.0 mg intravitreal ranibizumab for recalcitrant neovascular macular degeneration-primary end point. Ophthalmology 2013 Feb; 120(2): 349-54.

Gangaputra S, Almukhtar T, Glassman AR, Aiello LP, Bressler N, Bressler SB, Danis RP, Davis MD; Diabetic Retinopathy Clinical Research Network. Comparison of film and digital fundus photographs in eyes of individuals with diabetes mellitus. Invest Ophthalmol Vis Sci. 2011 Aug 3;52(9):6168-73.

E Chen, DM Brown, MS Benz, RH Fish, TP Wong, RY Kim, JC Major, Jr. Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy (the flying saucer sign). Clinical Ophthalmology 2010 Oct 21;4:1151-8.

E Chen, MS Benz, RH Fish, DM Brown, TP Wong, RY Kim, JC Major, Jr. Use of nepafenac (Nevanac™) in combination with intravitreal anti-VEGF agents in the treatment of recalcitrant exudative macular degeneration requiring monthly injections. Clinical Ophthalmology 2010 Oct 28;4:1249-52.

JC Major, Jr., M. Engelbert, H. Flynn, D. Miller, W.E. Smiddy, & J.L. Davis. Endophthalmitis caused by methicillin-resistant versus methicillin-sensitive Staphlococcus aureus: antibiotic susceptibilities and clinical outcomes. American Journal of Ophthalmology 2010 Feb;149(2):278-83.

M. Ruggeri, JC Major, Jr., C. McKeown, R.W. Knighton, C.A. Puliafito, & S. Jiao. Retinal Structure of Birds of Prey Revealed by Ultra-High Resolution Spectral-Domain Optical Coherence Tomography. Investigative Ophthalmology and Visual Science November 2010:51(11):5789-5795.

Suk KK, Berrocal AM, Murray TG, Rich R, Major JC, Hess D, Johnson RA. Retinal detachment despite aggressive management of aggressive posterior retinopathy of prematurity. J Pediatr Ophthalmol Strabismus 2010 Dec 22;47.

ER Holz & JC Major, Jr. An Algorithm for Management of Retinopathy of Prematurity Detachments. Vitreoretinal Surgery and Technology 2002;11(4):1,10-12.

O’Driscoll, B.J., O’Malley, R.E., and Clare, J.: Acne and Cellular Allergy. Excerpta Medical International Congress of Allergology, Florrence, 1970.

Easty, D., Dallas, N., O’Malley, R.E.: Aphakic Macular Edema Following Prosthetic Lens Implantation. British Journal of Ophthalmology, 61: 321, 1977.

McPherson, A., O’Malley, R.E., Bravo, J.: Retinal Detachment Following Late Posterior Capsulotomy. American Journal of Ophthalmology, 95: 593-7, 1983

McPherson, A., O’Malley, R.E., Beltangady, S.: Factors Influencing Post-Operative Visual Acuity in Retinal Detachment Patients with Macular Detachment. Annal of Ophthalmology, July 1984.

McPherson, A., O’Malley, R.E., Beltagandy, S.: Management of the Fellow Eye of Patients with Rhegmatogenous Retinal Detachment. Ophthalmology, 922-934, September 1984.

Orellana, J., O’Malley, R.E., McPherson, A., Font, R.: Pigmented Free- Floating Vitreous Cysts in Two Young Adults; electron microscopic observations. Ophthalmology, 92: 97-302, February 1985.

Schanzer, M.D., Font, R., O'Malley, R. E.: Primary Ocular Malignant Lymphoma Associated with Acquired Immune Deficiency Syndrome. Ophthalmology, 88-91, 1991.

O’Malley, R.E.: Vitrectomy in Retinopathy of Prematurity Aided by Baby- Sized lenses. Ocular Surgery News, Volume X, No. 6, March 1992.

Hawkins, W.R., O'Malley, R. E.: Vitrectomy and Indirect Ophthalmology. Ocular Surgery News, Volume II, No. 6, March 1993.

Mintz-Hittmer, M.D., Helen A., O'Malley, M.D., Ronan E., and Kretzer, Ph.D., Frank: Long- Term Form Identification Vision after Early, Closed Lensectomy - Vitrectomy for Stage 5 Retinopathy of Prematurity. Ophthalmology, Vol. 104. No. 3, March 1997.

Mintz - Hittner, M.D., Helen A., Miyashiro, M.D., Michael, Knight - Na nan, M.D., Donna, O'Malley, Ronan E. and Marlar Ph. D., Richard: Vitreoretinal Findings similar to Retinopathy of Prematurity in infants with Compound Heterozygous Protein S Deficiency. Ophthalmology, Vol. 106, No. 8, August 1999.

Peer-Reviewed Publications

Kim RS, Jain RR, Brown DM, Bretana ME, Kegley EN, Singer MA, Aragon AV, Schefler AC. Elevated Choroidal Thickness and Central Serous Chorioretinopathy in the Fellow Eyes of Patients with Circumscribed Choroidal Hemangioma. Ocular Oncology and Pathology. 2018; June: In press.

Schefler AC, Kim RS. Recent advancements in the management of retinoblastoma and uveal melanoma. F1000 Research. 2018; June: In press.

Berry D, Schefler AC, Seider M, Materin MA, Stinnett S, Mruthyunjaya P, for the Ocular Oncology Study Consortium. Correlation of gene expression profile status and American Joint Commision on Cancer Stage in Uveal Melanoma. Retina. 2018; June: In press.

Payne JF, Clark WL, Bruce BB, Treat & Extend Protocol in Patients with Diabetic Macular Edema Study Group (incl Schefler AC). Retinopathy progression with treat and extend ranibizumab for diabetic macular edema. Ophthalmology. 2018; May 2. pii: S0161-6420(18)30678-X. doi: 10.1016/j.ophtha.2018.03.046.

Kim RS, Chevez-Barrios P, Divatia M, Bretana ME, Teh B, Schefler AC. Yield, techniques, and complications of transvitreal and transscleral biopsies in small uveal melanoma. JAMA Ophthalmol. 2018 Mar 29. doi: 10.1001/jamaophthalmol.2018.0561.

Berry D, Seider M, Stinnett S, Mruthyunjaya P, Schefler AC for the Ocular Oncology Consortium. Relationship of clinical features and baseline tumor size with gene expression profile status in uveal melanoma: a multi-institutional study. Retina. 2018 Mar 23.

Jampol JM, Glassman AR, Liu D, and the Diabetic Retinopathy Clinical Research Network (DRCR) (incl Schefler AC). Plasma vascular endothelial growth factor concentrations after intravitreal anti-vascular endothelial growth factor therapy for diabetic macular edema. Ophthalmology. 2018; S0161-6420(17)32232-7.

Nguyen BT, Kim RS, Vretana ME, Kegley E, Schefler AC. Association between traditional clinical high-risk features and gene expression profile classification in uveal melanoma. Graefes Arch Clin Exp Ophthalmol. 2018; 256 (2): 421-427.

Francis JH, Abramson DH, Ji X, Shields CL, Teixeira LF, Schefler AC, Cassoux N,
Hadjistilianou D, Berry JL, Frenkel S, Munier FL. Risk of extraocular extension in eyes with retinoblastoma receiving intravenous chemotherapy. JAMA Ophthalmolo. 2017; 135 (12): 1426-1429.

Mruthyunjaya P, Seider MI, Stinnett S, Schefler AC; Ocular oncology study
consortium. Association between tumor regression rate and gene expression profile after Iodine 125 plaque radiotherapy for uveal melanoma. Ophthalmology. 2017; May: 2017 Oct;124(10):1532-1539.

Kim RS, Dannenbaum MJ, Lin MW, Bretana ME, Brown DL, Schefler AC. Use of Femoral artery ultrasound during intra-arterial chemotherapy for children under 10 kg with retinoblastoma. Retina. May: 2017. doi: 10.1097/IAE.0000000000001713.

Tann AW, Teh BS, Lewis GD, Scarboro SB, Bretana ME, Croft PC, Butler B, Chevez-Barrios P, Schefler AC. Early Outcomes of Uveal Melanoma Treated Using Modern Biopsy Techniques and Intraoperative Ultrasound Guidance: Local Tumor Control and Systemic Outcomes, Practical Radiation Oncology. 2017; 7 (4): e275-e282.

Abdelfattah NS, Al-Sheikh M, Pitetta S and the TREX-AMD Study Group (incl Schefler AC). Macular atrophy in neovascular age-related macular degeneration with monthly versus treat-and-extend ranibizumab: findings form the TREX-AMD trial. Ophthalmology. 2017; 124 (2): 215-223.

Kim RS, Chevez-Barrios P, Bretana ME, Wong TP, Teh BS, Schefler AC. Histopathologic analysis of transvitreal fine needle aspiration biopsy needle tracts for uveal melanoma. Am J Ophth. 2017; 174: 9-16.

Kim R, Dannenbaum MJ, Schefler AC. Intra-arterial chemotherapy for retinoblastoma: history, techniques, and update on outcomes. Retina Today. 2016; Jul/Aug: 65-70.

Li AL, Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC Jr, Brown DM, Schefler AC, Kim RY, O’Malley RE. Endophthalmitis after intravitreal injection: Role of prophylactic topical antibiotics. Retina. 2016; 36 (7): 1349-56.

Wells JA et al. and DRCR Network (incl. Schefler AC). Association of baseline visual acuity and retinal thickness with 1-year efficacy of Aflibercept, Bevacizumab, and Ranibuzab for diabetic macular edema. JAMA Ophthalmology. 2016; 134 (2): 127-134.

Wykoff CC, Croft DE, Brown DM, Wang R, Payne JF, Clark L, Abdelfattah NS, Sadda SR, Benz MS, Chen E, Fish RH, Johnson DL, Kim RY, Major JC Jr., O’Malley RE, Schefler AC, Shah AR, Vance SK, Wells JA 3rd, Wong TP. Prospective trial of treat-and-extend versus monthly dosing for neovascular age-related macular degeneration: TRex-AMD 1-Year results. Ophthalmology. 2015; 122: 2514-2522.

DRCR Network (incl. Schefler AC). Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema. N Engl J Med. 2015; 26; 372 (13): 1193-1203.

Schefler AC, Gologorsky D, Marr BP, Shields CL, Zeolite I, Abramson DH. Extraocular Extension of Uveal Melanoma After Fine Needle Aspiration, Vitrectomy, and Open Biopsy. JAMA Ophthalmol. 2013; 131 (9): 1220-1224.

Henry CR, Flynn HW Jr., Miller D, Schefler AC, Forster RK, Alfonso EC. Delayed-onset endophthalmitis associated with corneal suture infections. J Ophthalmic Inflamm Infect. 2013 Jun 11;3(1):51.

Schefler AC, Abramson DH. Update on Ophthalmic Oncology 2012: Advances in retinoblastoma and uveal melanoma. Asia Pacific Journal of Ophthalmology. 2013; 2 (2): 119-131.

Schefler AC. Retinoblastoma 2012. Retina Today. Dec 2012; 55-62.

Ayres B, Bretana ME, Dubovy S, Schefler AC. Mushroom shaped vasoproliferative tumor. Ophthalmic Surg Lasers Imaging. 2012; Oct 4;43 Online:e104-6.

Khan S, Khan S, Finger PT, Yu GP, Razzaq L, Jager MJ, de Keizer RJ, Sandkull P, Seregard S, Gologorsky D, Schefler AC, Murray TG, Kivelä T, Giuliari GP, McGowan H, Simpson ER, Corriveau C, Coupland SE, Damato BE. Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply. Arch Ophthalmol 2012; 130: 1229-1231.

Braich PS, Chag JS, Albini TA, Schefler AC. Irido-lenticular abscess as the initial sign of Candida albicans endogeonous endophthalmitis. Ophthalmic Surg Lasers Imaging 2011; Dec 8; 42 Online:e107-9.

Khan S, Finger PT, Yu GP, Razzaq L, Jager MJ, de Keizer RJ, Sandkull P, Seregard S, Gologorsky D, Schefler AC, Murray TG, Kivela T, Giulari GP, McGowan H, Simpson ER, Corriveau C, Coupland SE, Damato BE. Clinical and pathologic characteristics of biopsy-proven iris melanoma: a multicenter international study. Arch Ophthalmol 2011; 130(1):57-64.

Wykoff CC, Murray TG, Markow AM, Feun LG, Schefler AC, Gayer S. Preoperative evaluation for patients with choroidal/ciliary body melanomas: what is necessary? Am J Ophthalmol 2011; 151: 921-934.

Schefler AC, Flynn HW Jr. Pneumatic retinopexy for retinal detachment after macular hole surgery. Retinal Physician; January 2011: 51-54.

Houston SK, Pina Y, Clarke J, Koru-Sengal T, Scott WK, Nathanson L, Schefler AC, Murray TG. Regional and temporal differences in gene expression of LHBetaTag retinoblastoma tumors. Invest Ophthalmol Vis Sci 2011; In print.

Vajzovic LM, Murray TG, Aziz-Sultan MA, Schefler AC, Wolfe SQ, Hess D, Fernandes CE, Dubovy SR. Supraselective intra-arterial chemotherapy: evaluation of treatment-related complications in advanced retinoblastoma. Clin Ophthalmol 2011; 5: 171-176.

Houston SK, Pina Y, Murray TG, Boutrid H, Cebulla C, Schefler AC, Shi W, Celdran M, Feuer W, Merchan J, Lampidis TJ. Novel retinoblastoma treatment avoids chemotherapy: the effect of optimally timed combination therapy with angiogenic and glycolytic inhibitors on LHBetaTag retinoblastoma tumors. Clin Ophthalmol 2011; 5: 129-137.

Mutapcic L, Murray TG, Aziz-Sultan MA, Schefler AC, Fernandes CE, Quintero-Wolfe S, Hess DJ, Dubovy SR. Clinicopathologic review of enucleated eyes after intra-arterial chemotherapy with melphalan for advanced retinoblastoma. Archives of Ophthalmology 2010; 128: 1619-1623.

Gologorsky D, Schefler AC, Ehlies F, Raskauskas PA, Williams BK Jr., Murray TG. Clinical imaging and high-resolution ultrasonography in melanocytoma management. Clinical Ophthalmol 2010; 9: 855-859.

Pina Y, Boutrid H, Murray TG, Wolfe SQ, Schefler AC, Houston SK, Moftakhar R, Fernandes CE, Reichbach J, Aziz HA, Markoe AM, Aziz-Sultan MA. Ophthalmic vasculature alterations following systemic chemotherapy and periocular carboplatin treatment of advanced retinoblastoma. J Pediatr Ophthalmol Strabismus 2010; 22: 47 Online:e1-5.

Gologorsky D, Schefler AC, Williams BK Jr., Boutrid H, Dubovy SR, Murray TG. Medulloepithelioma: invasive versus noninvasive diagnostic methods and their impacts on outcome. Retinal Cases and Brief Reports. 2011; 5: 33-36.

Williams BK Jr., Schefler AC, Garonzik S, Gologorsky D, Shi W, Cavalcante L, Cavalcante M, Feuer W. Frequent prosthesis refitting to prevent implant exposure in patients with retinoblastoma. J Pediatr Ophthalmol Strabismus 2010; 23: 1-9.

Davis RP. Schefler AC, Murray TG. Concomitant bilateral anti-VEGF injections for the treatment of exudative age-related macular degeneration. Clin Ophthalmol. 2010 4: 703-707.

Williams BK Jr., Cebulla CM, Schefler AC, Fernandes CE, Gologorsky D, Murray TG. Required reduction in dose of chemotherapy due to Down Syndrome-associated chemosensitivity. Retinal Cases and Brief Reports 2010; 4: 59-61.

Cavalcante LL, Cavalcante ML, Murray TG, Vigoda MM, Pina Y, Decatur CL, Davis RP, Olmos LC, Schefler AC, Parrott MB, Alliman KJ, Flynn HW, Moshfeghi AA. Intravitreal injection analysis at the Bascom Palmer Eye Institute: evaluation of clinical indications for the treatment and incidence rates of endophthalmitis. Clin Ophthalmol 2010; 25: 519-524.

Leng T, Cebulla CM, Schefler AC, Murray TG. Focal periocular carboplatin chemotherapy avoids systemic chemotherapy for unilateral, progressive retinoblastoma. Retina 2010; 30: S66-68.

Sisk RA, Berrocal AM, Schefler AC, Dubovy SR, Bauer MS. Epiretinal membranes indicate a severe phenotype of neurofibromatosis type 2. Retina 2010; 30: S51-58.

Wykoff CC, Berrocal AM, Schefler AC, Uhlhorn SR, Ruggeri H, Hess D. Intraoperative OCT of a full-thickness macular hole before and after internal limiting membrane peeling. Ophthalmic Surg Lasers Imaging 2010; 41: 7-11.

Pina Y, Boutrid H, Murray TG, Jager MJ, Cebulla CM, Schefler AC, Ly LV, Alegret A, Celdran M, Feuer W, Jockovich ME. Impact of tumor-associated macrophages in LH(BETA)T(AG) mice on retinal tumor progression: relation to macrophage subtype. Invest Ophthalmol Vis Sci, 2010; 51: 2671-2677.

Schefler AC, Mutapcic L, Murray TG. Dubovy SR. Optic nerve invasion from anpmelanotic peripapillary choroidal melanoma. Retinal Cases and Brief Reports. 2009; 3:329-332.

Schefler AC. New insights into retinal diseases using imaging and functional techniques. Ophthalmology Report. Summer 2009; 3(1): 4-10.

Schefler AC, Murray TG, Shields JA. Brachytherapy for uveal melanoma: new developments and controversies. Retinal Physician, September 2009, 31-34.

Schefler AC, Murray TG, Markoe A. Radiotherapy in Ocular Oncology: Advances in brachytherapy for uveal melanoma. Retinal Physician, July 2009, 31-34.

Schefler AC, Gologorsky D, Murray TG. Primary intraocular lymphoma: an update on pathology and treatments, Retina Today, July 2009, 54-57.

Leng TS, Schefler AC, Murray TG. Retinal vascular tumor and peripheral vasculitis in the setting of systemic tuberculosis. Ophthalmic Surgery, Lasers, and Imaging. 2009; 40: 409-412.

Schefler AC, Pina Y, Boutrid H, Hernandez E, Jao S, Ruggeri M, Murray TG. Improvements in endolaser technology. Retina Today, April 2009, 68-70.

Pina Y, Boutrid H, Schefler AC, Dubovy SR, Feuer WJ, Jockovich ME, Murray TG. Blood vessel maturation in retinoblastoma tumors: spatial distribution of neovessels and mature vessels and its impact on ocular treatment. Invest Ophthalmol Vis Sci 2009; 50: 1020-1024.

Schefler AC, Abramson DH. Should evisceration ever be done in a blind, painful eye? Arch Ophthalmol. 2009; 127: 211-212.

Schefler AC, Abramson DH. Retinoblastoma: what is new in 2007-2008. Current Opinion in Ophthalmology. 2008; 19: 526-534.

Feilmeier MR, Lossos I, Schefler AC, Murray TG. Successful use of semi-nested PCR for the diagnosis of primary intraocular lymphoma. Leukemia and Lymphoma. 2008; 49: 1612-1615.

Cebulla C, Alegret AM, Feuer WJ, Shi W, Schefler AC, Murray TG. Tumor volume reduction using combined combined phacoemulsification and intravitreal triamcinolone injection. Journal of Cataract and Refractive Surgery. 2008; 34:1669-1673.

Vigoda MM, Gayer S, Tutiven J, Murtha M, Schefler AC, Murray TG. Targeting operating room inefficiencies in the complex management of retinoblastoma. Archives of Ophthalmology. 2008: 126: 1241-1243.

Bhatt AB, Schefler AC, Feuer WJ, Yoo SH, Murray TG. Comparison of predictions made by the intraocular lens master and ultrasound biometry. Archives of Ophthalmology. 2008: 126: 929-933.

Schefler AC, Berrocal AM, Murray TG. Advanced Coats’ disease: Management with repetitive aggressive laser ablation therapy. Retina. 2008; 28 Supplement: 538-541.

Schefler AC, Kleinerman R, Abramson DH. Second nonocular cancers in retinoblastoma. Expert Review of Ophthalmology. 2008; 3: 51-61.

Schefler AC, Dubovy SR, Berrocal AM. OCT Characteristics of epiretinal membranes in Neurofibromatosis 2. Ophthalmic Surgery Lasers and Imaging. 2008; 39: 73-77.

Schefler AC, Jockovich ME, Lossos IS, Toledano S, Feilmeier M, Dubovy SR, Murray TG. An Update on primary malignant intraocular tumors. Retinal Physician, October 2007; 37-45.

Gombos DS, Hungerford J, Abramson DH, Kingston J, Chantada G, Dunkel IJ, Antoneli CB, Greenwald M, Haik BG, Leal CA, Medina-Sanson A, Schefler AC, Veerakul G, Wieland R, Bornfeld N, Wilson MW, Yu CB. Secondary acute myelogenous leukemia in retinoblastoma: is chemotherapy a factor? Ophthalmology. 2007; 114: 1378-1383.

Schefler AC, Jockovich ME, Toledano S, Murray TG. Historical and modern approaches to chemotherapy for retinoblastoma: A review. Expert Review of Ophthalmology. 2006; 1: 83-95.

Schefler AC, Feuer W, Cicciarelli N, Toledano S, Murray TG. Macular retinoblastoma: evaluation of tumor control, local complications, and visual outcomes for eyes treated with chemotherapy and repetitive focal laser ablation. Ophthalmology. 2006; 114:162-169.

Abramson DH, Schefler AC. Correspondence: Reply. Retina. 2005; 25: 951-952.

Abramson DH, Schefler AC. Update on retinoblastoma. Retina. 2004; 24: 828-848.

Abramson DH, Schefler AC. Transpupillary thermotherapy as initial treatment for small intraocular retinoblastoma: technique and predictors of success. Ophthalmology. 2004; 111: 984-991.

Schefler AC, Shields CL, Shields JA, Demirci H, Maus M, Eagle RC Jr. Lacrimal sac lymphoma in a child. Archives of Ophthalmology. 2003; 121: 1330-1333.

Abramson DH, Schefler AC, Almeida D, Folberg R. Optic nerve tissue shrinkage during pathologic processing after enucleation for retinoblastoma. Archives of Ophthalmology. 2002; 121: 73-75.

Abramson DH, Schefler AC, Beaverson KL, Rollins IS, Ruddat MS, Kelly CJ. Rapid growth of retinoblastoma in a premature twin. Archives of Ophthalmology. 2002; 120: 1232-1233.

Bilsky MH, Schefler AC, Sandberg DI, Rosenblum MK. Sclerosing epithelioid fibrosarcoma involving the neuraxis. Neurosurgery 2000; 47: 956-959.

Non-Peer Reviewed Publications

Harbour JW, Correa Z, Aaberg TM, Kim IK, Mruthyunjaya PM, Schefler AC. Suspicious choroidal melanocytic tumors – how useful are those risk factors anyway? Retina Times. Fall 2016.

George RT, Leveque CM, Schefler AC. On the Case: Race for the Cure. Millenium Eye. Jul/Aug 2016.

Kim RS, Dannenbaum MJ, Schefler AC. Intraarterial Chemotherapy for Retinoblastoma: history, technique, and updates on outcomes. Retina Today. Jul/Aug 2016.

Schefler AC, Mruthyunjaya PM. Fine Needle Aspiration Biopsy for Uveal Melanoma. Part 2: Genetic testing techniques and controversies. Retinal Physician. Oct 2015: 57-60.

Schefler AC, Mruthyunjaya PM. Fine Needle Aspiration Biopsy for Uveal Melanoma. Part 1: Technique and complications. Retinal Physician. July/Aug 2015: 54-57.

Hess D, Schefler AC. The Importance of ophthalmic photography in the diagnosis of ocular tumors. J Ophthalmic Photography. 2009; 31: 118-128.

Schefler AC, Berrocal AM. Infant presents with leukocoria, retinal detachment. Ophthalmology Times. 2006; 31: 52-53.

Shah AR, Weng CY. Billing & Coding Basics for Early Career Retina Specialist. Retina Times. Summer 2019. (In Press)

Shah AR. Keeping Current with Retinal Coding. Retinal Physician 2019 May:2-3. (In Press)

Major JC, Lampen S, Wykoff CC, Lampen S, Ou WC, Brown DM, Wong TP, Shah AR. The Texas Taco Technique for Inverted Internal Limiting Membrane Flap in Large Full Thickness Macular Holes: A Short Term Pilot Study. Retina 2018 Dec 31. doi: 10.1097/IAE.0000000000002431 (Epub ahead of Print).

Storey PP, Tauqeer Z, Yonekawa Y, Todorich B, Wolfe JD, Shah SP, Shah AR, Koto T, Abbey AM, Morizane Y, Sharma P, Wood EH, Morizane-Hosokawa M, Pendri P, Pancholy M, Harkey S, Jeng-Miller KW, Obeid A, Borkar DS, Chen E, Williams P, Okada AA, Inoue M, Shiraga F, Hirakata A, Shah CP, Prenner J, Garg S; Post-Injection Endophthalmitis (PIE) Study Group. The Impact of Preefilled Syringes on Endophthalmitis Following Intravitreal Injection of Ranibizumab. Am J Ophthalmol. 2019 Mar;199:200-208. doi: 10.1016/j.ajo.2018.11.023. Epub 2018 Dec 13.

Abdelfattah NS, Hariri AH, Al-Sheikh M, Pitetta S, Ebraheem A, Wykoff CC, Sadda SR; TREX-AMD Study Group. Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial. Am J Ophthalmol. 2018 Aug;192:84-90.

Amram AL, Mandviwala M, Ou W, Wykoff CC, Shah AR. Predictors of Visual Acuity Outcomes Following Vitrectomy for Idiopathic Macular Hole. Ophthalmic Surgery, Lasers and Imaging Retina. 2018 Aug 1;49(8):566-570.

Payne JF, Clark WL, Bruce BB, Wykoff CC, Brown DM, Menke BM, Iverson SM, Allen KF, Boyer DS; Treat & Extend Protocol in Patients with Diabetic Macular Edema Study Group. Retinopathy Regression with Treat and Extend Ranibizumab for Diabetic Macular Edema. Ophthalmology. 2018 Aug;125(8):1304-1306.

Naik S, Wykoff CC, Ou WC, Stevenson J, Gupta S, Shah AR. Identification of Factors to Increase Efficacy of Telemedicine Screening for Diabetic Retinopathy in Endocrinology Practices Using the Intelligent Retinal Imaging System (IRIS) Platform. Diabetes Res Clin Pract. 2018 Jun;140:265-270.

Sultan H, Wykoff CC, Shah AR. 5-year outcomes of surgically treated symptomatic epiretinal membranes with and without internal limiting membrane peeling. Ophthalmic Surgery, Lasers and Imaging Retina. 2018 May 1;49(5):296-302.

Hasbrook, M, Yonekawa Y, Van Laere L, Shah AR, Capone A Jr. Bilateral Persistent Fetal Vasculature and COX15 Mutation. Canadian Journal of Ophthalmology. 2017 Dec;52(6):e203-e205.

Abbey AM, Huang LY, Shah AR, Hassan TS. Recurrent Macular Holes in the Era of Small gauge Vitrectomy: A Review of Incidence, Risk Factors, and Outcomes. Retina 2017 May;37(5):921-924.

Shah AR, Yonekawa Y, Todorich B, Van Laere L, Hussain R, Woodward MA, Abbey AM, Wolfe JD. Prediction of Anti-VEGF Response in Diabetic Macular Edema After 1 Injection. Journal of VitreoRetinal Diseases. 2017 Feb;1(3): 169-174.

Yoshihiro Y, Ashkan AM, Van Laere L, Shah AR, Thomas BJ, Ruby AJ, Faia LJ. Stalagmite-like Preretinal Inflammatory Deposits in Vitrectomized Eyes with Posterior Uveitis. Digital Journal of Ophthalmology. 2017 Feb;23(1): 1-3.

Hussain RM, Abbey AM, Shah AR, Drenser KA, Trese MT, Capone A Jr. Chorioretinal Coloboma Complications: Retinal Detachment and Choroidal Neovascular Membrane. Journal of Ophthalmic and Vision Research. 2017 Jan;12(1): 3-10.

Shah AR. Widefield Fundus Photography and Imaging in Diabetic Retinopathy. Diabetic Eye Disease Consults. 2016 Sep;2(1): 1, 9-10.

Shah AR, Abbey AM, Yonekawa Y, Khandan S, Wolfe JD, Trese MT, Williams GA, Capone A Jr. Widefield Fluorescein Angiography in Patients without Peripheral Disease: A Study of Normal Peripheral Findings. Retina 2016 Jun;36(6):1087-92.

Shah AR, Xi A, Ashkan AM, Yonekawa Y, Faia LJ, Hassan TS, Ruby A, Wolfe JD. Short-Term Efficacy of Intravitreal Dexamethasone Implant in Vitrectomized Eyes With Recalcitrant Diabetic Macular Edema Previously Treated with Anti-VEGF Therapy. Journal of Ophthalmic and Vision Research. 2016 Apr-Jun;11(2):183-7.

Wolfe JD, Shah AR, Alfaran A, Yonekawa Y, Ashkan AM, Capone A Jr. Receiver Operating Characteristics Curve to Predict Anti-VEGF Resistance in Retinal Vein Occlusions, and Efficacy of Ozurdex. European Journal of Ophthalmology. 2016 Mar-Apr;26(2):168-73.

Wykoff CC, Croft DE, Brown DM, Wang R, Payne JF, Clark L, Abdelfattah NS, Sadda SR; TREX-AMD Study Group. Prospective Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: TREX-AMD 1-Year Results. Ophthalmology. 2015 Dec;122(12):2514-22.

Shah AR. Widefield Imaging Finds its Place in the Practice. Retinal Specialist. 2015 Nov: 30-32.

Mammo D, Yonekawa Y, Thomas BT, Shah AR, Abbey AM, Trese MT, Drenser KA, Capone A Jr. Association of Autosomal Dominant Familial Exudative Vitreoretinopathy and Spinal Muscular Atrophy. European Journal of Ophthalmology. 2015 Oct 21;25(6):e116-8.

Shah AR, Wolfe JD. Updates on Stage 3 Meaningful Use for EHR. Retinal Physician. 2015 May;12: 36,68.
Capone A Jr, Shah AR, Abbey AM, Drenser KA, Trese MT. Widefield Imaging in Pediatric Retinal Disease. Retinal Today. 2015 March; 10:42-44.

Rao P, Abbey AM, Yonekawa Y, Shah AR, Capone A Jr., Trese MT, Drenser KA. Macular Cavernous Hemangioma Associated with Peripheral Vascular Anomalies & Nonperfusion. OSLI Retina 2015 Jul 1;46(7):764-7.

Yonekawa Y, Abbey AM, Shah AR, Thomas BJ, Williams GA, Faia L. Sutureless transconjunctival cannula-based scleral PCIOL fixation. [Surgical video, accepted].

Rao P, Shah AR, Michelotti M, Anderson B, Abbey AM, Jain N, Stec L, Lowe L, Johnson MW, Williams GA. Bilateral Acute Endopthalmitis Associated with Munchausen Syndrome. Retinal Cases and Brief Reports. 2015 Spring;9(2):177-80.

Shah AR, Abbey AM, Williams GA. Evolving Surgical Management of Rhegmatogenous Retinal Detachments. Current Surgery Reports. 2015 Jan;3(3):1-5.

Abbey AM, Hussain RM, Shah AR, Wolfe JD, Faia LJ, Williams GA. Sutureless scleral fixation of intraocular lenses: outcomes of two approaches. The 2014 Yasuo Tano Memorial Lecture. Graefes Ophthalmology Jan;253(1):1-5.

Yonekawa Y, Abbey AM, Shah AR, Capone A Jr. Endoilluminator Phototoxic Maculopathy Associated with Combined ICG-Assisted Epiretinal Membrane and Internal Limiting Membrane Peeling. Clinical Ophthalmology Dec 9;8:2501-6.

Damani MR, Shah AR, Karp CL, Orlin SE. Treatment of Ocular Surface Squamous Neoplasia with Topical Aloe Vera Drops. Cornea, 2014 Jan;34(1):87-9.

Ghodasra D, Eftekhari K, Shah AR, VanderBeek BL. Outcomes, Impact on Management and Costs of Fungal Eye Disease Consults in a Tertiary Care Setting. Ophthalmology, 2014 Dec;121(12):2334-9.

Shah AR, Tamhankar M. Optic Neuropathy Associated With Copper Deficiency After Gastric Bypass Surgery. Retinal Cases and Brief Reports, Winter 2014 8(1):73-76.

Shah AR, Zaidi A, Brucker AJ. Serous Retinal Detachments Associated with Light Chain Deposition Disease. Retinal Cases and Brief Reports, Summer 2013 7(3):236-241.

Maguire MG, Daniel E, Shah AR, Grunwald JE, Hagstrom S, Avery R, Huang J, Martin RW, Roth DB, Castellarin AA, Fine SL, Martin DF. Incidence of Choroidal Neovascularization in the Fellow Eye Among Patients Treated with Ranibizumab or Bevacizumab in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology, 2013 Oct;120(10):2035-41.

Shah AR, Ruggiero J. Endogenous Candida Endophthalmitis. Retina, 2013 Feb;33(2):453-4.
Liu TYA, Shah AR, Del Priore, LV. Progression of Lesion Size in Untreated Eyes with Exudative Age-related Macular Degeneration: A Meta-analysis Using Lineweaver-Burk Plots. JAMA Ophthalmology, 2013 Mar 1;131(3):335-40.

Shah AR, Del Priore LV. Natural History of Predominantly Classic, Minimally Classic, and Occult Subgroups in Exudative Age-related Macular Degeneration. Ophthalmology, 2009 Oct;116(10):1901-7.

Shah AR, Del Priore LV. Duration of Action of Intravitreal Ranibizumab and Bevacizumab in Exudative AMD Eyes Based on Macular Volume Measurements. British J Ophthalmology, 2009 Aug;93(8): 1027-32.

Shah AR, Del Priore LV. Subfoveal exudative age-related macular degeneration: evidence for preoccult disease. Current Opinion Ophthalmology, 2009 May;20(3): 182-7.

Shah AR, Del Priore LV. Progressive Visual Loss in Subfoveal Exudation in Age-Related Macular Degeneration: A Meta-analysis Using Lineweaver-Burke Plots. Am J Ophthalmology, 2007 Jan;143(1):83-89

Lee IT, Lampen SIR, Wong TP, Major JC Jr, Wykoff CC. Fovea-sparing rhegmatogenous retinal detachments: impact of clinical factors including time to surgery on visual and anatomic outcomes. Graefes Arch Clin Exp Ophthalmol. 2019 Jan 11.

Major JC Jr, Lampen SIR, Wykoff CC, Ou WC, Brown DM, Wong TP, Shah AR. THE TEXAS TACO TECHNIQUE FOR INTERNAL LIMITING MEMBRANE FLAP IN LARGE FULL-THICKNESS MACULAR HOLES: A Short-Term Pilot Study. Retina. 2018 Dec 31.

Keenan TD, Agrón E, Domalpally A, Clemons TE, van Asten F, Wong WT, Danis RG, Sadda S, Rosenfeld PJ, Klein ML, Ratnapriya R, Swaroop A, Ferris FL 3rd, Chew EY; AREDS2 Research Group. Progression of Geographic Atrophy in Age-related MacularDegeneration: AREDS2 Report Number 16. Ophthalmology. 2018 Dec;125(12):1913-1928.

Brown DM, Ou WC, Wong TP, Kim RY, Croft DE, Wykoff CC; DAVE Study Group. Targeted Retinal Photocoagulation for Diabetic Macular Edema with Peripheral Retinal Nonperfusion: Three-Year Randomized DAVE Trial. Ophthalmology. 2018 May;125(5):683-690.

Kim RS, Chevez-Barrios P, Bretana ME, Wong TP, Teh BS, Schefler AC. Histopathologic Analysis of Transvitreal Fine Needle Aspiration Biopsy Needle Tracts for Uveal Melanoma. Am J Ophthalmol. 2017 Feb;174:9-16. PMID 27818205.

Khurana RN, Wykoff CC, Bansal AS, Akiyama K, Palmer JD, Chen E, Chang LK, Major JC Jr, Wu C, Wang R, Croft DE, Wong TP. THE ASSOCIATION OF EPIRETINAL MEMBRANE WITH MACULAR HOLE FORMATION AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR. Retina. 2016 Sep 14. [Epub ahead of print] PMID: 27632712.

Li AL, Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC Jr, Brown DM, Schefler AC, Kim RY, OʼMalley RE. ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION: Role of Prophylactic Topical Ophthalmic Antibiotics. Retina. 2016 Jul;36(7):1349-56. PMID: 26655622.

Brown DM, Wykoff CC, Croft DE, Wong TP; RAVE Study Group.. Reply: To PMID 24914476. Retina. 2015 Oct;35(10):e61-3. PubMed PMID: 26398558.

Wykoff CC, Brown DM, Croft DE, Major JC Jr, Wong TP. Progressive retinal nonperfusion in ischemic central retinal vein occlusion. Retina. 2015 Jan;35(1):43-7. PubMed PMID: 25102193.

Brown DM, Wykoff CC, Wong TP, Mariani AF, Croft DE, Schuetzle KL; RAVE Study Group.. Ranibizumab in preproliferative (ischemic) central retinal vein occlusion: the rubeosis anti-VEGF (RAVE) trial. Retina. 2014 Sep;34(9):1728-35. PubMed PMID: 24914476.

Wykoff CC, Brown DM, Croft DE, Wong TP: Two Year SAVE Outcomes: 2.0 mg Ranibizumab for Recalcitrant Neovascular AMD. Ophthalmology. 2013 Sep;120(9):1945-1946.e1. PMID 24001533

Wykoff CC, Brown DM, Chen E, Major JC, Croft DE, Mariani A, Wong TP; SAVE Study Group. SAVE (Super-dose anti-VEGF) Trial: 2.0 mg Ranibizumab for Recalcitrant Neovascular Age-Related Macular Degeneration: 1-Year Results. Ophthalmic Surg Lasers Imaging Retina. 2013 Mar-Apr;44(2):121-6. PMID 23510037

Chen, EC, Benz, MS, Fish, RH, Brown, DM, Wong, TP, Kim, RY, Major, JC: Use of Nepafenac (Nevanac®) in Combination with Intravitreal Anti-VEGF Agents in the Treatment of Recalcitrant Exudative Macular Degeneration Requiring Monthly Injections. Clin Ophthalmol. 2010 Oct 28; 4: 1249–1252. PMID 21151329

Chen, EC, Brown, DM, Benz, MS, Fish, RH, Wong, TP, Kim, RY, Major, JC: Spectral Domain Optical Coherence Tomography as an Effective Screening Test for Hydroxychloroquine Retinopathy (The “Flying Saucer” Sign). Clin Ophthalmol. 2010 Oct 21; 4:1151-8. PMID 21060664

Chen, EC, Brown, DM, Wong, TP, Benz, MS, et al: Lucentis® using Visudyne® Study: Determining the Threshold-dose Fluence of Verteporfin Photodynamic Therapy Combined with Intravitreal Ranibizumab for Exudative Macular Degeneration. Ophthalmology Clinics. 2010, 4: 1073-79. PMID 20957143

Luviano DM, Benz MS, Kim RY, Fish RH, Wong TP, Kegley EN, Brown DM: Selected Clinical Comparisons of Spectral Domain and Time Domain Optical Coherence Tomography. Ophthalmic Surg Lasers Imaging. 2009 May-Jun;40(3):325-8. PMID 19485303
Brown, DM, Beardsley, RM, Fish, RH, Wong, TP, Kim, RY: Long-Term Stability of Circumferential Silicone Sponge Scleral Buckling Exoplants. Retina. 2006, 26: 645-649. OMID 16829806

Byrnes, GA, Leen, M, Wong, TP, Benson, WE: Pars Plana Vitrectomy for Ciliary Block (malignant) Glaucoma. Ophthalmology. 1995, 102: 1308-1311. PMID 9097767

Phillips II, WB, Wong, TP, Bergren RL, et al: Late Onset Endophthalmitis in Association with Filtering Blebs. Ophthalmic Surgery. 1994 Feb;25: 88-91. PMID 8183519

Dugan, JD, Repke, C, Wong, TP, et al: Massive Spontaneous Subretinal Hemorrhage From a Choroidal Metastasis. American Journal of Ophthalmology. 1993 May 15; 115(5)677-9. PMID 8488927

Wong, TP: Posterior Segment Manifestations of Lyme Disease. Ophthalmic Surgery. 1989, 20: 154-6.

Peer Reviewed Manuscripts

Wykoff CC, Le RT, Khurana RN, Brown DM, Ou WC, Wang R, Clark WL, Boyer DS. Outcomes with As-Needed Aflibercept and Macular Laser Following the Phase III VISTA DME Trial: ENDURANCE 12-Month Extension Study. Americal Journal of Ophthalmology. 2016 In Press.

Abdelfattah NS, Al-Sheikh M, Pitetta S, Mousa A, Sadda SR, Wykoff CC. Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX Randomized Trial. Ophthalmology. 2016 In Press.

Payne JF, Wykoff CC, Clark WL, Bruce BB, Boyer DS, Brown DM. Randomized Trial of Treat & Extend Ranibizumab With & Without Navigated Laser for Diabetic Macular Edema: TREX-DME 1 Year Outcomes. Ophthalmology. 2016 In Press.

Khurana RN, Wykoff CC, Bansal AS, Akiyama K, Palmer JD, Chen E, Chang LK, Major JC Jr, Wu C, Wang R, Croft DE, Wong TP. The Association of Epiretinal Membrane with Macular Hole Formation After Rhegmatogenous Retinal Detachment Repair. Retina 2016, Sep 14 (Epub ahead of print)

Croft DE, Wykoff CC, Michels S, Chakravarthy U, Cruess AL. Regulatory Factors Influencing Usage of Retinal Pharmaceuticals: A look both home and abroad. American Journal of Ophthalmology. 2016. In Press.

Wykoff CC, Elman MJ, Regillo C, Ding B, Lu N, Stoilov I. Predictors of Diabetic Macular Edema Treatment Frequency with Ranibizumab During the Open-Label Extension of the RIDE and RISE Trials. Ophthalmology. 2016; Epub ahead of Print.

Corvi F, Lattanzio R, Miserocchi E, Querques L, Bandello F, Querques G, Croft DC, Wykoff CC. Diagnostic and Therapeutic Challenges. RETINA. 2016 Feb 23; Epub ahead of Print.

Wykoff CC, Hariprasad SM. DRCR Protocol-T: Reconciling 1- and 2-Year Data for Managing Diabetic Macular Edema. Ophthalmic Surgery Lasers & Imaging Retina. 2016; 47(4):308-12.

Wang R, Wykoff CC, Brown DM. Granular Hyperreflective Specks by Spectral Domain Optical Coherence Tomography as Signs of West Nile Virus Infection: The Stardust Sign. Retina Cases & Brief Reports. 2015 [Epub ahead of print].

Li AL, Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC, Brown DM, Schefler AC, Kim RY, O’Malley RE. Endophthalmitis After Intravitreal Injection: Role of Prophylactic Topical Ophthalmic Antibiotics. RETINA. 2016; 36(7):1349-56.

Wang R, Wykoff CC, Christie L, Croft DE, Major JC, Fish RH, Brown DM. Choroidal Neovascularization Secondary to Alexandrite Laser Exposure. Retina Cases & Brief Reports. 2016;10(3):244-8.

DRCR Network. Wells JA, Glassman AR, Jampol LM, et al. Association of Baseline Visual Acuity and Retinal Thickness with 1-Year Efficacy of Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema. JAMA Ophthalmology. 2016;134(2):127-34.

Wykoff CC, Croft DE, Brown DM, Wang R, Payne JF, Clark L, Abdelfattah NS, Sadda, SR. Prospective Trial of Treat & Extend versus Monthly Dosing for Neovascular Age Related Macular Degeneration: TREX-AMD 1-Year Results. Ophthalmology. 2015;122(12):2514-22.

Wykoff CC, Schwartz SG, Adelman, RA, Brucker AJ, Flynn HW. Primary rhegmatogenous retinal detachment repair: evidence supports an individualized approach. British Journal of Ophthalmology. 2015;99(11):1451-3.

Major JC, Wykoff CC, Croft DE, Wang R, Mariani AF, Lehmann AE, Brown DM. Aflibercept for pigment epithelial detachment for previously treated neovascular age-related macular degeneration. Canadian Journal of Ophthalmology. 2015;50(5):373-7.

Croft DE, Wykoff CC, Hemert JV, Verhoek M, Brown DM. Not All Retina Is Created Equal – Functional and Metabolic Quantification of Ultra-Widefield Images. Ophthalmology. 2015. June 26, ePub Ahead of Press
Brown DM, Wykoff CC, Croft DE, Wong TP. Response to Letter by Calugaru. RETINA. 2015;35(10):61-3.

Wykoff CC, Hariprasad SM. Comparing Aflibercept, Bevacizumab, and Ranibizumab for DME: Analysis of DRCR Protocol T. Ophthalmic Surgery Lasers & Imaging Retina. 2015; 46(3):302-5.

DRCR Network. Wells JA, Glassman AR, Ayala AR, et al. Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema. New England Journal of Medicine. 2015;372(13):1193-203

Silva RA, Sridhar J, Miller D, Wykoff CC, Flynn HW Jr. Exogenous Fungal Endophthalmitis: An Analysis of Isolates and Susceptibilities to antifungal agents over a 20-year period (1990-2010). Am J Ophthalmology. 2015;159(2):257-264.

Wykoff CC, Brown DM, Croft DE, Major JC Jr., Wong TP. Progressive Retinal Nonperfusion in Ischemic Central Retinal Vein Occlusion. RETINA. 2015;35(1):43-7.

Campochiaro PA, Wykoff CC, Singer M, Johnson R, Marcus D, Yau L, Sternberg G. Monthly vs As-Needed Ranibizumab Injections in Patients with Retinal Vein Occlusion: The SHORE Study. Ophthalmology. 2014;121(12):2432-42.

Croft DE, Hemert JV, Wykoff CC, Clifton D, Verhoek M, Fleming A, Brown DM. Precise Montaging and Metric Quantification of Retinal Surface Area from Ultra-Widefield Fundus Photography and Fluorescein Angiography. Ophthalmic Surgery Lasers & Imaging Retina. 2014;45(4):312-7.

Brown DM, Wykoff CC, Wong TP, Mariani AF, Croft DE, Schuetzle KL; RAVE Study Group. Ranibizumab in Pre-Proliferative (Ischemic) Central Retinal Vein Occlusion: The Rubeosis Anti- VEgf (RAVE) Trial. RETINA. 2014;34(9):1728-35.

Campochiaro PA, Wykoff CC, Shapiro H, Ehrlich J, Rubio R. Neutralization of Vascular Endothelial Growth Factor Slows Progression of Posterior Retinal Nonperfusion in Patients with Diabetic Macular Edema. Ophthalmology. 2014;121(9):1783-9.

Wykoff CC, Brown DM, Maldonado ME, Croft DE. Aflibercept treatment for patients with exudative age-related macular degeneration who were incomplete responders to multiple ranibizumab injections (TURF trial) British Journal of Ophthalmology. 2014;98(7):951-5.

Major JC, Wykoff CC, Mariani AF, Chen E, Croft DE, Brown DM. Comparison of spectral-domain and time-domain optical coherence tomography in the detection of neovascular age-related macular degeneration activity. RETINA. 2014;34(1):48-54.
Wykoff CC, Flynn HW Jr, Scott IU. What is the optimal timing for rhegmatogenous retinal detachment repair? JAMA Ophthalmology. 2013;131(11):1399-400.

Wykoff CC, Brown DM, Croft DE, Wong TP. Two year SAVE outcomes: 2.0 mg ranibizumab for recalcitrant neovascular age-related macular degeneration. Ophthalmology. 2013;120(9):1945-6.

Wykoff CC, Brown DM, Chen E, Major JC, Croft DE, Mariani AF, Wong TP. SAVE (Super-dose anti-VEGF) trial: 2.0 mg ranibizumab for recalcitrant neovascular age-related macular degeneration: 1-year results. Ophthalmic Surgery Lasers & Imaging Retina. 2013;44(2):121-6.

Mariani AF, Major JC, Brown DM, Wykoff CC, Benz MS, Kegley EN. Purtscher-like Retinopathy Associated with Pemphigus Vulgaris. Retina Cases & Brief Reports. 2013;7(4):304-6.

Houston SK, Wykoff CC, Berrocal AM, Hess DJ, Murray TG. Laser for the treatment of intraocular tumors. Lasers Med Sci. 2013;28(3):1025-34.

Houston SK, Wykoff CC, Berrocal AM, Hess DJ, Murray TG. Laser treatment for retinopathy of prematurity. Lasers Med Sci. 2013;28(2):683-92.

Lingappan A, Wykoff CC, Albini TA, Miller D, Pathengay A, Davis JL, Flynn HW Jr. Endogenous fungal endophthalmitis: causative organisms, management strategies, and visual acuity outcomes. American Journal of Ophthalmology. 2012;153(1):162-6

Bielory BP, Dubovy SR, Sinclair JC, Wykoff CC, Murray TG. Pseudohypopyon as a clinical manifestation in metastatic lung carcinoma. Ophthalmic Surg Lasers Imaging. 2012;9:43:1-4.

Wykoff CC, Flynn HW Jr, Rosenfeld PJ. Prophylaxis for endophthalmitis following intravitreal injection: antisepsis and antibiotics. American Journal of Ophthalmology. 2011;152(5):717-719.

Wykoff CC, Flynn HW Jr. Endophthalmitis after intravitreal injection: prevention and management. RETINA. 2011;31(4):633-635.

Wykoff CC, Murray TG, Markoe AM, Feun LG, Schefler AC, Gayer S. Preoperative evaluation for patients with choroidal/ciliary body melanomas: what is necessary? American Journal of Ophthalmology. 2011;151(6):921-924.

Wykoff CC, Flynn HW Jr, Han DP. Allergy to povidone-iodine & cephalosporins: the clinical dilemma in ophthalmic use. American Journal of Ophthalmology. 2011;151(1):4-6.

Wykoff CC, Houston SK, Berrocal AM. Anti-vascular endothelial growth factor agents for pediatric retinal diseases. Int Ophthalmol Clin. 2011;51(1):185-199.

Wykoff CC, Parrott MB, Flynn HW Jr, Shi W, Miller D, Alfonso EC. Nosocomial acute-onset postoperative endophthalmitis at a university teaching hospital (2002-2009). American Journal of Ophthalmology. 2010;150(3):392-398. Reply 2011;151(4):733.

Wykoff CC, Smiddy WE, Mathen T, Schwartz SG, Flynn HW Jr, Shi W. Fovea-sparing retinal detachments: time to surgery and visual outcomes. American Journal of Ophthalmology. 2010;150(2):205-10.

Wykoff CC, Berrocal AM, Schefler AC, Uhlhorn SR, Ruggeri M, Hess D. Intraoperative OCT of a full-thickness macular hole before and after internal limiting membrane peeling. Ophthalmic Surgery Lasers & Imaging. 2010;41(1):7-11. With cover illustration.

Wykoff CC, Albini T, Couvillion SS, Dubovy S, Davis J. Intraocular cryptococcoma. Archives of Ophthalmology. 2009;127(5):700-702. With cover illustration.

Sisk RA, Wykoff CC, Albini TA. Comment on “fundus autofluorescence and multiple evanescent white dot syndrome.” RETINA. 2009;29(9):1377-1378.
Wykoff CC, Dubovy SR, Barredo JC, Murray TG. Simultaneous presentation of retinoblastoma and morning glory disc anomaly. Retina Cases & Brief Reports. 2009;3(3):354-357.

Couvillion SS, Wykoff CC, Tutiven JL, Schaefer A, Murray TG. Diffuse neonatal hemangiomatosis presenting as bilateral iris hemangiomas in an infant. Retina Cases & Brief Reports. 2009;3(3):279-282.

Wykoff CC, Lujan BJ, Rosenfeld PJ. Photodynamic therapy of bullous central serous chorioretinopathy with subretinal exudate and a tear of the retinal pigment epithelium. Retina Cases & Brief Reports. 2009;3(2):218-223.

Wykoff CC, Flynn HW Jr., Miller D, Scott IU, Alfonso EC. Exogenous fungal endophthalmitis: microbiology and clinical outcomes. Ophthalmology. 2008;115(9):1501-1507. With cover illustration.

Wykoff CC, Lam BL, Brathwaite CD, Biegel JA, McKeown CA, Rosenblum MK, Allewelt HB, Sandberg DI. Atypical teratoid / rhabdoid tumor arising from the third cranial nerve. J of Neuroophthalmology. 2008;28(3):207-211.

Wykoff CC, Pineda R. Myopic laser in situ keratomileusis (LASIK) in eyes with thick corneas. J Cataract and Refractive Surgery. 2006;32(5):900-901.

Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (HIF) in regulating HIF transcriptional target genes. J Biol Chem. 2004;279(41):42719-42725.

Turley H, Wykoff CC, Troup S, Watson PH, Gatter KC, Harris AL. The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissue and tumors. J Pathol. 2004;203(3):808-813.

Wykoff CC, Sotiriou C, Cockman ME, Ratcliffe PJ, Maxwell P, Liu E, Harris AL. Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene. Br J Cancer. 2004;90(6):1235-1243.

Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, Gatter KC, Harris AL. DEC1 (STRA13) protein expression relates to hypoxia-inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. J Path. 2003;200(2):222-228.

Watson PH, Chia SK, Wykoff CC, Han C, Leek RD, Sly WS, Gatter KC, Ratcliffe P, Harris AL. Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma. Br J Cancer. 2003; 88(7):1065-1070.

Swinson DE, Jones JL, Richardson D, Wykoff CC, Turley H, Pastorek J, Taub N, Harris AL, O'Byrne KJ. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small cell lung cancer. J Clin Oncol. 2003;21(3):473-482.

Adeyinka A, Emberley E, Niu Y, Snell L, Murphy LC, Sowter H, Wykoff CC, Harris AL, Watson PH. Analysis of gene expression in ductal carcinoma in situ of the breast. Clin Cancer Research. 2002;8(12):3788-3795.

Mandriota SJ, Turner KJ, Davies DR, Murray PG, Morgan NV, Sowter HM, Wykoff CC, Maher ER, Harris AL, Ratcliffe PJ, Maxwell PH. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell. 2002;1(5):459-468.

Turner KJ, Crew JP, Wykoff CC, Watson PH, Poulsom R, Pastorek J, Ratcliffe PJ, Cranston D, Harris AL. The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer. Br J Cancer. 2002; 86(8):1276-1282.

Wykoff CC, Beasley N, Watson PH, Campo L, Chia SK, English R, Pastorek J, Sly WS, Ratcliffe P, Harris AL. Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast. Am J Pathol. 2001;158:1011-1019.

Beasley NJ, Wykoff CC, Watson PH, Leek R, Turley H, Gatter K, Pastorek J, Cox GJ, Ratcliffe P, Harris AL. Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density. Cancer Research. 2001;61(13):5262-5267.

Chia SK, Wykoff CC, Watson PH, Han C, Leek RD, Pastorek J, Gatter KC, Ratcliffe P, Harris AL. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. J Clin Oncology. 2001;19(16):3660-3668.

Koukourakis MI, Giatromanolaki A, Sivridis E, Simopoulos K, Pastorek J, Wykoff CC, Gatter KC, Harris AL. Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy. Clin Cancer Research. 2001;7(11):3399-3403.

Giatromanolaki A, Koukourakis MI, Sivridis E, Pastorek J, Wykoff CC, Gatter KC, Harris AL. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Research. 2001;61(21):7992-7998.

Loncaster JA, Harris AL, Davidson SE, Logue JP, Hunter RD, Wykoff CC, Pastorek J, Ratcliffe PJ, Stratford IJ, West CM. Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix. Cancer Research. 2001;61(17):6394-6399.

Wykoff CC, Beasley NJ, Watson PH, Turner KJ, Pastorek J, Sibtain A, Wilson GD, Turley H, Talks KL, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Research. 2000;60(24):7075-7083.

Wykoff CC, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ. Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumor suppressor by mRNA differential expression profiling. Oncogene. 2000;19(54):6297-6305.

Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999;399(6733):271-275.

Pugh CW, Chang GW, Cockman M, Epstein AC, Gleadle JM, Maxwell PH, Nicholls LG, O'Rourke JF, Ratcliffe PJ, Raybould EC, Tian YM, Wiesener MS, Wood M, Wykoff CC, Yeates KM. Regulation of gene expression by oxygen levels in mammalian cells. Adv. Neprol Necker Hosp. 1999;29:191-206.

Engelman JA, Wykoff CC, Yasuhara S, Song KS, Okamoto T, Lisanti MP, Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth. J Biol Chem. 1997;272(26):16374-16381.

Publications

Matthew S. Benz, M.D.

David M. Brown, M.D.

Eric Chen, M.D.

Publications (Journals)

Publications (Clinical Trial Papers)

Richard H. Fish, M.D.

Christopher R. Henry, M.D.

Rosa Y. Kim, M.D.

James C. Major, Jr., M.D., PhD

Journal Articles

Ronan E. O’Malley, M.D.

Amy C. Schefler, M.D.

Peer-Reviewed Publications

Non-Peer Reviewed Publications

Ankoor R. Shah, M.D.

Tien P. Wong, M.D.

Charles C. Wykoff, M.D., PhD

Peer Reviewed Manuscripts

Now Open: New Schertz Clinic & Research Center

Now Open: New Schertz Clinic & Research Center